Impact of chest trauma and overweight on mortality and outcome in severely injured patients

  • The morbidity and mortality of severely injured patients are commonly affected by multiple factors. Especially, severe chest trauma has been shown to be a significant factor in considering outcome. Contemporaneously, weight-associated endocrinological, haematological, and metabolic deviations from the norm seem to have an impact on the posttraumatic course. Therefore, the aim of this study was to determine the influence of body weight on severely injured patients by emphasizing chest trauma. A total of 338 severely injured patients were included. Multivariate regression analyses were performed on patients with severe chest trauma (AIS ≥ 3) and patients with minor chest trauma (AIS < 3). The influence of body weight on in-hospital mortality was evaluated. Of all the patients, 70.4% were male, the median age was 52 years (IQR 36–68), the overall Injury Severity Score (ISS) was 24 points (IQR 17–29), and a median BMI of 25.1 points (IQR 23–28) was determined. In general, chest trauma was associated with prolonged ventilation, prolonged ICU treatment, and increased mortality. For overweight patients with severe chest trauma, an independent survival benefit was found (OR 0.158; p = 0.037). Overweight seems to have an impact on the mortality of severely injured patients with combined chest trauma. Potentially, a nutritive advantage or still-unknown immunological aspects in these patients affecting the intensive treatment course could be argued.

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Author:Thurid Eckhardt, Klemens Horst, Philipp StörmannORCiDGND, Felix Marius BläsiusORCiDGND, Martijn Hofman, Christian Herren, Philipp Kobbe, Frank HildebrandORCiDGND, Hagen AndruszkowORCiDGND
URN:urn:nbn:de:hebis:30:3-551988
DOI:https://doi.org/10.3390/jcm9092752
ISSN:2077-0383
Parent Title (English):Journal of Clinical Medicine
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of Publication (online):2020/08/26
Date of first Publication:2020/08/26
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2020/09/14
Tag:chest trauma; eight disorders; obesity; outcome; overweight
Volume:6
Issue:(9), art. 2752
Page Number:8
HeBIS-PPN:469758341
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0