PINK1 and Ataxin-2 as modifiers of growth

  • A recent report showed PINK1 transcript levels to be up- or down-regulated by the gain or loss of Ataxin-2 function, respectively, in human blood, in a human neural cell line and in mouse tissues. These observations may have profound implications for the regulation of cell growth and may be medically exploited for the treatment of cancer and neural atrophy...

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Author:Nesli Ece ŞenGND, Suzana Gispert, Georg AuburgerORCiDGND
URN:urn:nbn:de:hebis:30:3-441221
DOI:https://doi.org/10.18632/oncotarget.16636
ISSN:1949-2553
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/28430647
Parent Title (English):OncoTarget
Publisher:Impact Journals LLC
Place of publication:[s. l.]
Document Type:Article
Language:English
Date of Publication (online):2017/05/22
Date of first Publication:2017/03/28
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/05/22
Tag:motor neuron disease; neuroblastoma regression; obesity; tumor suppressor
Volume:8
Issue:20
Page Number:2
First Page:32382
Last Page:32383
Note:
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HeBIS-PPN:421385154
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 3.0