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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-517162
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.51716
Zusammenfassung
Imidazole glycerol phosphate synthase (HisFH) is a heterodimeric bienzyme complex operating at a central branch point of metabolism. HisFH is responsible for the HisH-catalyzed hydrolysis of glutamine to glutamate and ammonia, which is then used for a cyclase reaction by HisF. The HisFH complex is allosterically regulated but the underlying mechanism is not well understood. Here, we elucidate the ...
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