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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-26721
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.2672
Zusammenfassung
Imidazolylpropylguanidines derived from impromidine and arpromidine are more potent and efficacious agonists at the guinea pig histamine H₂ receptor (gpH₂R) than at the human H₂R (hH₂R) in the GTPase assay. Additionally, such guanidines are histamine H₁ receptor (H₁R) antagonists with preference for the human relative to the guinea pig receptor. The purpose of this study was to examine ...