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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-205403
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.20540
Zusammenfassung
The expression of the two Epstein-Barr virus (EBV) major membrane proteins gp250/350 (MA-BLLF1) on the surface of recombinant CHO clones cannot be amplified by methotrexate (MTX) selection, perhaps due to toxic effects of these membrane proteins. After removal of sequences encoding the part of the glycoproteins responsible for membrane anchorage, the gp250/350 is secreted into the medium. ...
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