- AutorIn
- Johanna Elisabeth Köhler
- Titel
- Effekte von Telemedizin auf depressive Symptome und Lebensqualität bei Patienten mit chronischer Herzinsuffizienz – eine prästratifizierte Subgruppenanalyse der Telemedical Interventional Monitoring in Heart Failure (TIM-HF) study
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-770985
- Datum der Einreichung
- 17.03.2021
- Datum der Verteidigung
- 18.11.2021
- Abstract (EN)
- Aims: Depression is a frequent comorbidity in patients with chronic heart failure (CHF). Telemonitoring has emerged as a novel option in CHF care. However, patients with depression have been excluded in most telemedicine studies. This pre-specified subgroup analysis of the Telemedical Interventional Monitoring in Heart Failure (TIM-HF) trial investigates the effect of telemonitoring on depressive symptoms over a period of 12months. Methods and results: The TIM-HF study randomly assigned 710 patients with CHF to either usual care (UC) or a telemedical intervention (TM) using non-invasive devices for daily monitoring electrocardiogram, blood pressure and body weight. Depression was evaluated by the 9-item Patient Health Questionnaire (PHQ-9) with scores ≥10 defining clinically relevant depressive symptoms. Mixed model repeated measures were performed to calculate changes in PHQ-9 score. Quality of life was measured by the Short Form-36. At baseline, 156 patients had a PHQ-9 score ≥10 points (TM: 79, UC: 77) with a mean of 13.2 points indicating moderate depressiveness. Patients randomized to telemedicine showed an improvement of their PHQ-9 scores, whereas UC patients remained constant (P = 0.004). Quality of life parameters were improved in the TM group compared to UC. Adjustment was performed for follow-up, New York Heart Association class, medication, age, current living status, number of hospitalizations within the last 12months and serum creatinine. In the study population without depression, the PHQ-9 score was similar at baseline and follow-up. Conclusion Telemedical care improved depressive symptoms and had a positive influence on quality of life in patients with CHF and moderate depression.
- Freie Schlagwörter (DE)
- Herzinsuffizienz, Depression, Telemedizin, Lebensqualität
- Klassifikation (DDC)
- 610
- Den akademischen Grad verleihende / prüfende Institution
- Universität Leipzig, Leipzig
- Version / Begutachtungsstatus
- angenommene Version / Postprint / Autorenversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-770985
- Veröffentlichungsdatum Qucosa
- 22.12.2021
- Dokumenttyp
- Dissertation
- Sprache des Dokumentes
- Deutsch
- Lizenz / Rechtehinweis
- CC BY-NC-ND 4.0