- AutorIn
- Jasmin Flemming Technischen Universität Dresden, Universitätsklinikum Carl Gustav Carus, Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Germany
- Christian HannigTechnischen Universität Dresden, Universitätsklinikum Carl Gustav Carus, Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Germany
- Matthias HannigClinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Homburg
- Titel
- Caries Management - The Role of Surface Interactions in De- and Remineralization-Processes
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-903768
- Quellenangabe
- Journal of Clinical Medicine : open access journal
Erscheinungsjahr: 2022
Jahrgang: 11
Heft: 23
Seiten: 1-22
E-ISSN: 2077-0383
Artikelnummer: 7044 - Erstveröffentlichung
- 2022
- Abstract (EN)
- Background: Bioadhesion and surface interactions on enamel are of essential relevance for initiation, progression and prevention of caries and erosions. Salivary proteins on and within initial carious and erosive lesions can facilitate or aggravate de- and remineralization. This applies for the pellicle layer, the subsurface pellicle and for proteins within initial carious lesions. Little is known about these proteinaceous structures related to initial caries and erosion. Accordingly, there is a considerable demand for an understanding of the underlying processes occurring at the interface between the tooth surface and the oral cavity in order to develop novel agents that limit and modulate caries and erosion. Objectives and findings: The present paper depicts the current knowledge of the processes occurring at the interface of the tooth surface and the oral fluids. Proteinaceous layers on dental hard tissues can prevent or aggravate demineralization processes, whereas proteins within initial erosive or carious lesions might hinder remineralization considerably and restrict the entry of ions into lesions. Conclusions: Despite the fact that organic–inorganic surface interactions are of essential relevance for de- and remineralization processes at the tooth surface, there is limited knowledge on these clinically relevant phenomena. Accordingly, intensive research is necessary to develop new approaches in preventive dentistry.
- Andere Ausgabe
- Link zum Artikel, der zuerst in „Journal of Clinical Medicine” erschienen ist
DOI: 10.3390/jcm11237044 - Freie Schlagwörter (DE)
- organisch-anorganische Wechselwirkungen, erworbenes Schmelzpellikel, Zahnerosion, Proteine, Biofilm-Management
- Freie Schlagwörter (EN)
- organic–inorganic interactions, acquired enamel pellicle, dental erosion, proteins, biofilm management
- Klassifikation (DDC)
- 610
- Verlag
- MDPI, Basel
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-903768
- Veröffentlichungsdatum Qucosa
- 22.03.2024
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
- CC BY 4.0