- AutorIn
- Charlotte Zerna Technische Universität Dresden, Department of Neurology, University Hospital Carl Gustav Carus, Dresden, Germany
- Timo SiepmannTechnische Universität Dresden, Department of Neurology, University Hospital Carl Gustav Carus, Dresden, Germany
- Kristian BarlinnTechnische Universität Dresden, Department of Neurology, University Hospital Carl Gustav Carus, Dresden, Germany
- Jessica Kepplinger
- Lars-Peder Pallesen
- Volker Pütz
- Ulf Bodechtel
- Titel
- Association of time on outcome after intravenous thrombolysis in the elderly in a telestroke network
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-356366
- Quellenangabe
- Journal of Telemedicine and Telecare Erscheinungsort: London
Verlag: Sage
Erscheinungsjahr: 2016
Jahrgang: 22
Heft: 1
Seiten: 18-24
E-ISSN: 1758-1109 - Erstveröffentlichung
- 2016
- Abstract (EN)
- Background: Recent studies showed that the safety and benefit of early intravenous (IV) thrombolysis on favourable outcomes in acute ischemic stroke are also seen in the elderly. Furthermore, it has shown that age increases times for pre- and in-hospital procedures. We aimed to assess the applicability of these findings to telestroke. Methods: We retrospectively analysed 542 of 1659 screened consecutive stroke patients treated with IV thrombolysis in our telestroke network in East-Saxony, Germany from 2007 to 2012. Outcome data were symptomatic intracranial hemorrhage (sICH) by ECASS-2-criteria, survival at discharge and favourable outcome, defined as a modified Rankin scale (mRS) of 0–2 at discharge. Results: Thirty-three percent of patients were older than 80 years (elderly). Being elderly was associated with higher risk of sICH (p¼0.003), less favourable outcomes (p¼0.02) and higher mortality (p¼0.01). Using logistic regression analysis, earlier onsetto-treatment time was associated with favourable outcomes in not elderly patients (adjusted odds ratio (OR) 1.18; 95% CI 1.03–1.34; p¼0.01), and tended to be associated with favourable outcomes (adjusted OR 1.13; 95% CI 0.92–1.38; p¼0.25) and less sICH (adjusted OR 0.88; 95% CI 0.76–1.03; p¼0.11) in elderly patients. Age caused no significant differences in onset-to-doortime (p¼0.25), door-to-treatment-time (p¼0.06) or onset-to-treatment-time (p¼0.29). Conclusion: Treatment time seems to be critical for favourable outcome after acute ischemic stroke in the elderly. Age is not associated with longer delivery times for thrombolysis in telestroke.
- Andere Ausgabe
- Link zum Artikel, der zuerst in der Zeitschrift 'Journal of Telemedicine and Telecare' erschienen ist.
DOI: 10.1177/1357633X15585241 - Freie Schlagwörter (DE)
- Telemedizin, Thrombolyse, Ischämischer Schlaganfall, akute Schlaganfalltherapie, Epidemiologie, Schlaganfallanlagen
- Freie Schlagwörter (EN)
- Telemedicine, thrombolysis, ischemic stroke, acute stroke therapy, epidemiology, stroke facilities
- Klassifikation (DDC)
- 610
- Verlag
- Sage, London
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-356366
- Veröffentlichungsdatum Qucosa
- 09.10.2019
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis