- AutorIn
- Judith Hahner Technische Universität Dresden, Institute of Materials Science, Germany#Leibniz-Institut für Polymerforschung Dresden e. V., Germany
- Claudia HinüberTechnische Universität Dresden, Institute of Materials Science, Germany#Leibniz-Institut für Polymerforschung Dresden e. V., Germany
- Annette BreierLeibniz-Institut für Polymerforschung Dresden e. V., Germany
- Tobias Siebert
- Harald Brünig
- Gert Heinrich
- Titel
- Adjusting the mechanical behavior of embroidered scaffolds to lapin anterior cruciate ligaments by varying the thread materials
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-354017
- Quellenangabe
- Textile Research Journal Erscheinungsort: London
Verlag: Sage
Erscheinungsjahr: 2015
Jahrgang: 85
Heft: 14
Seiten: 1431-1444
E-ISSN: 1746-7748 - Erstveröffentlichung
- 2015
- Abstract (EN)
- Traumatic rupture of the anterior cruciate ligament (ACL) can cause local destabilization and loss of mobility. Reconstruction using engineered ACL grafts is rarely successful due to sub-optimal material choice and mechanical performance. Thus, the presented work demonstrates the fabrication of various embroidered single- and bi-component scaffolds made of two commercially available monofilament threads (polydioxanone, poly(lactic acid-co-ɛ- caprolactone)) as well as a novel melt spun poly(L-lactic acid) multifilament and their mechanical analysis by tensile tests and under cyclic loading. Selected scaffolds, adjusted by material composition and textile parameters, revealed a load–strain behavior comparable to native lapin ACL tissue exhibiting a sufficient amount of elastic deformation within the toe-region of 1.7%, scaffold stiffness of 123 N/mm and adequate maximum tensile load (300 N) and strain (20%). Therefore, the design of resorbable embroidered bi-component scaffolds represents a promising approach to replace artificial non-resorbable ligament grafts and allows for innovative tissue engineering strategies.
- Andere Ausgabe
- Link zum Artikel, der zuerst in der Zeitschrift 'Textile Research Journal' erschienen ist.
DOI: 10.1177/0040517514566107 - Freie Schlagwörter (DE)
- Stickereitechnik, mechanische Eigenschaften, ACL, Kaninchen, Struktureigenschaften, Gerüst, medizinische Textilien
- Freie Schlagwörter (EN)
- embroidery technology, mechanical properties, ACL, rabbit, structure properties, scaffold, medical textiles
- Klassifikation (DDC)
- 660, 670
- Verlag
- Sage, London
- Förder- / Projektangaben
- Deutsche Forschungsgemeinschaft ID: HE 4466/22-1
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-354017
- Veröffentlichungsdatum Qucosa
- 17.09.2019
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis