Retrospectively assessed trajectories of PTSD symptoms and their subsequent comorbidities.

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_91F02C4FA927
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Retrospectively assessed trajectories of PTSD symptoms and their subsequent comorbidities.
Journal
Journal of psychiatric research
Author(s)
Xu Y., Vandeleur C., Müller M., Seifritz E., Kleim B., von Känel R., Wagner E.N., Strippoli M.F., Castelao E., Gholamrezaee M.M., Preisig M., Ajdacic-Gross V.
ISSN
1879-1379 (Electronic)
ISSN-L
0022-3956
Publication state
Published
Issued date
04/2021
Peer-reviewed
Oui
Volume
136
Pages
71-79
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Dynamic trajectories of psychopathology, such as post-traumatic stress disorder (PTSD) provide a key to understanding human adjustment processes after trauma exposure. Recent studies have suggested more heterogeneous mental health outcomes than the initially identified four adjustment trajectories. To explore this heterogeneity, we investigated the after-trauma adjustment patterns of psychopathology based on retrospective lifetime data. This was first carried out on the PTSD symptoms (PTSS, including no symptoms, few symptoms, partial and full PTSD), and secondly together with their post-trauma comorbidities.
Data of trauma and the post-trauma mental disorders were collected for a large and randomly selected community sample, resulting in a N = 960 trauma-exposed subsample. Pattern recognition as carried out by latent class analysis (LCA) was implemented on this subsample. LCA was first exploited to identify the potential trajectory patterns of PTSS and next to explore the patterns of mental adjustments when additional post-trauma comorbid disorders, such as anxiety, mood and substance use disorders, were assessed.
Four PTSS trajectory patterns were found, namely resilient, chronic, recovered, and delayed onset, consistent with findings from longitudinal PTSD studies. When post-trauma comorbidities were evaluated, other than the trajectory pattern of delayed onset which retained a low comorbidity profile, the other three split respectively and paired up with either low, moderate or high comorbidity profile.
Mental health outcomes after trauma exposure were considerably more complex than the four previously established adjustment trajectories. Here, we uncovered additional and more heterogeneous adjustment patterns comprised of PTSS trajectories and post-trauma comorbidity profiles.
Keywords
PTSD comorbidity, PTSD symptom Trajectory, Post-trauma comorbidity profile, Resilience
Pubmed
Web of science
Open Access
Yes
Create date
15/02/2021 17:38
Last modification date
21/07/2022 7:11
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