Low incidence of community-acquired pneumonia among human immunodeficiency virus-infected patients after interruption of Pneumocystis carinii pneumonia prophylaxis.

Eigenmann, C.; Flepp, M.; Bernasconi, E.; Schiffer, V.; Telenti, A.; Bucher, H.; Wagels, T.; Egger, M.; Furrer, H.

doi:10.1086/368190

Low incidence of community-acquired pneumonia among human immunodeficiency virus-infected patients after interruption of Pneumocystis carinii pneumonia prophylaxis.

Details

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State: Public
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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.

Serval ID

serval:BIB_27237

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Low incidence of community-acquired pneumonia among human immunodeficiency virus-infected patients after interruption of Pneumocystis carinii pneumonia prophylaxis.

Journal

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

Author(s)

Eigenmann C., Flepp M., Bernasconi E., Schiffer V., Telenti A., Bucher H., Wagels T., Egger M., Furrer H.

Working group(s)

Swiss HIV Cohort Study

ISSN

1537-6591 (Electronic)

ISSN-L

1058-4838

Publication state

Published

Issued date

2003

Peer-reviewed

Oui

Volume

Number

Pages

917-921

Language

english

Notes

Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish

Abstract

We compared the incidence of bacterial pneumonia among 336 patients who discontinued trimethoprim-sulfamethoxazole (TMP-SMX) as prophylaxis against Pneumocystis carinii pneumonia (PCP) with that among 75 patients who fulfilled the criteria for discontinuation but continued receiving prophylaxis. The difference in the overall incidence rates for the 2 groups (1.2 events per 100 person-years) was not statistically significant. Discontinuation of TMP-SMX prophylaxis against PCP is not associated with a significant increase in the incidence of bacterial pneumonia among patients with a sustained CD4 cell count increase to >200 cells/microL.

Keywords

AIDS-Related Opportunistic Infections/microbiology, AIDS-Related Opportunistic Infections/prevention & control, Adult, Aged, Chemoprevention, Community-Acquired Infections/epidemiology, Female, Follow-Up Studies, HIV Infections/complications, Homosexuality, Male, Humans, Incidence, Male, Middle Aged, Pneumonia, Pneumocystis/prevention & control

URN

urn:nbn:ch:serval-BIB_272371

OAI-PMH

oai:serval.unil.ch:BIB_27237

DOI

10.1086/368190

Pubmed

12652393

Web of science

000181761700014

Open Access

Yes