Book/Dissertation / PhD Thesis

FZJ-2022-02080

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Role of secondary metabolites in antiphage defense in Streptomyces

Hardy, A. (Corresponding author)FZJ*

2022
Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag Jülich
ISBN: 978-3-95806-633-5

Please use a persistent id in citations: http://hdl.handle.net/2128/31547  urn:nbn:de:0001-2022083102

Abstract: Bacteriophages (phages) are viruses preying on bacteria and as such pose a major and ubiquitousthreat to bacterial communities. To cope with viral challenges, bacteria have evolved a diversifiedarsenal of defense systems. However, this repertoire is known to rely predominantly on protein orRNA effectors. On the other hand, bacteria produce an extraordinary diversity of secondarymetabolites, whose physiological function is often unknown. In this thesis, we explore the role ofbacterial secondary metabolites in the defense against phage predation. To this end, we used as amodel system Streptomyces, a prolific producer of secondary metabolites

Note: Biotechnologie 1
Note: Dissertation, HHU Duesseldorf, 2022

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Contributing Institute(s):

1. Biotechnologie (IBG-1)

Research Program(s):

1. 2171 - Biological and environmental resources for sustainable use (POF4-217) (POF4-217)

Appears in the scientific report 2022

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Database coverage:
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