- AutorIn
- Laura Florentina Steller
- Titel
- Engineering of Light-Gated Artificial Ion Channels
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:swb:14-1169805885137-06514
- Datum der Einreichung
- 14.11.2006
- Datum der Verteidigung
- 18.12.2006
- Abstract (EN)
- The goal of this project is the development of artificial ion channels that can be actuated by light and thus controlled efficiently. Our artificial system is composed of two regions: the gate and the body part. The gate part is based on light-responsive azo groups while the body part is formed by calix[4]resorcinarene. Key of controlling mechanism is the conformational change between cis and trans isomers, which is translated into movement of the gate. Light-gated artificial ion channels are aimed at eliminating of the stochastic mechanism of artificial ion channels. Such a reversible photocontrol should be a powerful tool for using artificial ion channels as the basis for the development of new pharmaceuticals and drug delivery systems, as photoswitches, and in the field of microfluidics.
- Freie Schlagwörter (DE)
- künstliche Ionenkanäle, Calixresorcinarene, photogesteuerter Verschluss, Patch Clamp
- Freie Schlagwörter (EN)
- artificial ion channel, calixresorcinarene, light switchable gate, patch clamp
- Klassifikation (DDC)
- 540
- Klassifikation (RVK)
- WE 5460
- Normschlagwörter (GND)
- Ionenkanal, Patch-Clamp-Methode
- GutachterIn
- Prof. Dr. rer. nat. habil. Reiner Salzer
- Doz. Dr. rer. nat. habil. Wolf Dieter Habicher
- Prof. Dr. rer. nat. habil. Kari Rissanen
- BetreuerIn
- Prof. Dr. rer. nat. habil. Reiner Salzer
- Verlag
- Technische Universität Dresden, Dresden
- URN Qucosa
- urn:nbn:de:swb:14-1169805885137-06514
- Veröffentlichungsdatum Qucosa
- 26.01.2007
- Dokumenttyp
- Dissertation
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis