EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution
- This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on themineralization of calciumphosphate from bulk aqueous solution. Mineralization was performed between pH 6 and 9 and with NTA or EDTA concentrations of 0, 5, 10, and 15 mM. X-ray diffraction and infrared spectroscopy show that at low pH, mainly brushite precipitates and at higher pH, mostly hydroxyapatite forms. Both additives alter the morphology of the precipitates. Without additive, brushite precipitates as large plates. With NTA, the morphology changes to an unusual rod-like shape. With EDTA, the edges of the particles are rounded and disk-like particles form. Conductivity and pH measurements suggest that the final products form through several intermediate steps.
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| Author details: | Doreen HentrichORCiDGND, Klaus TauerORCiD, Montserrat Espanol, Maria-Pau GinebraORCiD, Andreas TaubertORCiDGND |
|---|---|
| URN: | urn:nbn:de:kobv:517-opus4-469186 |
| DOI: | https://doi.org/10.25932/publishup-46918 |
| ISSN: | 1866-8372 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/31105185 |
| Title of parent work (German): | Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe |
| Publication series (Volume number): | Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (1095) |
| Publication type: | Postprint |
| Language: | English |
| Date of first publication: | 2021/01/13 |
| Publication year: | 2017 |
| Publishing institution: | Universität Potsdam |
| Release date: | 2021/01/13 |
| Tag: | EDTA; NTA; biomimetic mineralization; biomineralization; brushite; calcium phosphate; hydroxyapatite; precipitation |
| Issue: | 1095 |
| Number of pages: | 23 |
| Source: | Biomimetics 2 (2017) 4, Art. 24 DOI: 10.3390/biomimetics2040024 |
| Funding institution: | University of Potsdam; Max Planck Institute of Colloids and Interfaces |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
| DDC classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Peer review: | Referiert |
| Publishing method: | Open Access |
| Open Access / Gold Open-Access | |
| DOAJ gelistet | |
| License (German): |  CC-BY - Namensnennung 4.0 International |
| External remark: | Bibliographieeintrag der Originalveröffentlichung/Quelle |
