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Titel:Synthese von neuartigen, Disulfid-verknüpften, bioabbaubaren Polyethylenglykol-Polyethylenimin-Copolymeren zur Anwendung in der Gentherapie
Autor:Zhao, Nan
Weitere Beteiligte: Kissel, Thomas (Prof. Dr.)
Veröffentlicht:2010
URI:https://archiv.ub.uni-marburg.de/diss/z2010/0469
DOI: https://doi.org/10.17192/z2010.0469
URN: urn:nbn:de:hebis:04-z2010-04695
DDC: Chemie
Titel (trans.):Synthesis of noval disulfide containing biodegradable Polyethylenglycol-Polyethylenimine-copolymers for the Application in gene therapy
Publikationsdatum:2010-08-10
Lizenz:https://rightsstatements.org/vocab/InC-NC/1.0/

Dokument

Schlagwörter:
Gentherapie, gene therapy

Zusammenfassung:
In der vorliegenden Dissertation wird die Synthese der neuartigen, disulfid-verbrückten, bioabbaubaren PEG-PEI-Copolymeren als nicht-virale Vektoren zur Gentherapie beschrieben. Die DNA-Polyplexe der Copolymere wurden charakterisiert und auf ihre Eignung als Genvektoren für die in-vivo-Anwendung untersucht

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