Previous research has established that the integration of mobile technologies and related mobile applications in mathematics education can enhance learning in various ways. Additionally, there is a growing body of literature that recognises the importance of the usability of educational mobile applications. Thus, it is important to study how these mobile applications can be designed and developed in order to best support the impact on educational achievements. This paper presents an overview of possible usability issues of mobile graphing calculator applications and provides recommendations on how to overcome these concerns. The contribution of this paper is to propose helpful suggestions for designers and developers of mobile mathematics applications in order to develop easy to use applications that best support mobile technology enhanced learning in mathematics education.