Autism symptoms in Attention-Deficit/Hyperactivity Disorder : a familial trait which correlates with conduct, oppositional defiant, language and motor disorders

It is hypothesised that autism symptoms are present in Attention-Deficit/Hyperactivity Disorder (ADHD), are familial and index subtypes of ADHD. Autism symptoms were compared in 821 ADHD probands, 1050 siblings and 149 controls. Shared familiality of autism symptoms and ADHD was calculated using DeFries-Fulker analysis. Autism symptoms were higher in probands than siblings or controls, and higher in male siblings than male controls. Autism symptoms were familial, partly shared with familiality of ADHD in males. Latent class analysis using SCQ-score yielded five classes; Class 1(31%) had few autism symptoms and low comorbidity; Classes 2–4 were intermediate; Class 5(7%) had high autism symptoms and comorbidity. Thus autism symptoms in ADHD represent a familial trait associated with increased neurodevelopmental and oppositional/conduct disorders.

Vorschau

Einordnung

Datum der Veröffentlichung:
02.09.2011
URN:
urn:nbn:de:hbz:464-20110902-100642-2
DOI:
10.1007/s10803-008-0621-3
Sprache:
Englisch
Ressourcentyp:
Text
Kollektion:
E-Publikationen
Dewey Dezimal-Klassifikation:
610 Medizin und Gesundheit
Sachgruppen der Deutschen Nationalbibliographie:
610 Medizin, Gesundheit
Einrichtung:
Medizinische Fakultät, Universitätsklinikum Essen, LVR-Klinikum Essen, Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters
Informationen zur Erstveröffentlichung:

This is the reformatted manuscript submitted version of this article:

Mulligan, A., Anney, R.J.L., O’Regan, M. et al. Autism symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders. J Autism Dev Disord 39, 197–209 (2009). DOI: https://doi.org/10.1007/s10803-008-0621-3

The final version was published on 19 July 2008 and is available at: https://doi.org/10.1007/s10803-008-0621-3

Versionskennzeichen:
Reformatted Manuscript Submitted

Zitieren

Zitierform:
Zitierform konnte nicht geladen werden.

Rechte

Nutzung und Vervielfältigung:
Alle Rechte vorbehalten