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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-430347
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.43034
Zusammenfassung
In vitro chondrogenically differentiated mesenchymal stem cells (MSCs) have a tendency to undergo hypertrophy, mirroring the fate of transient "chondrocytes" in the growth plate. As hypertrophy would result in ossification, this fact limits their use in cartilage tissue engineering applications. During limb development, retinoic acid receptor (RAR) signaling exerts an important influence on cell ...
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