Laparoscopic appendectomy versus antibiotic treatment for acute appendicitis-a systematic review

Please always quote using this URN: urn:nbn:de:bvb:20-opus-266616
  • Background Over the last years, laparoscopic appendectomy has progressively replaced open appendectomy and become the current gold standard treatment for suspected, uncomplicated appendicitis. At the same time, though, it is an ongoing discussion that antibiotic therapy can be an equivalent treatment for patients with uncomplicated appendicitis. The aim of this systematic review was to determine the safety and efficacy of antibiotic therapy and compare it to the laparoscopic appendectomy for acute, uncomplicated appendicitis. Methods TheBackground Over the last years, laparoscopic appendectomy has progressively replaced open appendectomy and become the current gold standard treatment for suspected, uncomplicated appendicitis. At the same time, though, it is an ongoing discussion that antibiotic therapy can be an equivalent treatment for patients with uncomplicated appendicitis. The aim of this systematic review was to determine the safety and efficacy of antibiotic therapy and compare it to the laparoscopic appendectomy for acute, uncomplicated appendicitis. Methods The PubMed database, Embase database, and Cochrane library were scanned for studies comparing laparoscopic appendectomy with antibiotic treatment. Two independent reviewers performed the study selection and data extraction. The primary endpoint was defined as successful treatment of appendicitis. Secondary endpoints were pain intensity, duration of hospitalization, absence from work, and incidence of complications. Results No studies were found that exclusively compared laparoscopic appendectomy with antibiotic treatment for acute, uncomplicated appendicitis. Conclusions To date, there are no studies comparing antibiotic treatment to laparoscopic appendectomy for patients with acute uncomplicated appendicitis, thus emphasizing the lack of evidence and need for further investigation.show moreshow less

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Metadaten
Author: Franziska Köhler, Anne Hendricks, Carolin Kastner, Sophie Müller, Kevin Boerner, Johanna C. Wagner, Johan F. Lock, Armin Wiegering
URN:urn:nbn:de:bvb:20-opus-266616
Document Type:Journal article
Faculties:Medizinische Fakultät / Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie (Chirurgische Klinik I)
Fakultät für Biologie / Theodor-Boveri-Institut für Biowissenschaften
Medizinische Fakultät / Comprehensive Cancer Center Mainfranken
Language:English
Parent Title (English):International Journal of Colorectal Disease
ISSN:1432-1262
Year of Completion:2021
Volume:36
Issue:10
Pagenumber:2283–2286
Source:International Journal of Colorectal Disease 2021, 36(10):2283–2286. DOI: 10.1007/s00384-021-03927-5
DOI:https://doi.org/10.1007/s00384-021-03927-5
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/33852068
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Tag:acute appendicitis; antibiotics; laparoscopic appendectomy; open appendectomy
Release Date:2022/06/02
Licence (German):License LogoCC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International