- AutorIn
- Anne Freund
- Niels van Royen
- Karl B. Kern
- Alexander Jobs
- Holger Thiele
- Jorrit S. Lemkes
- Steffen Desch
- Titel
- Early coronary angiography in patients after out‐of‐hospital cardiac arrest without ST‐segment elevation
- Untertitel
- Meta‐analysis of randomized controlled trials
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-888481
- Quellenangabe
- Catheterization and Cardiovascular Interventions
Erscheinungsjahr: 2022
Jahrgang: 100
Seiten: 330-337 - Erstveröffentlichung
- 2022
- Abstract (EN)
- Objectives: To compare early coronary angiography to a delayed or selective approach in out‐of‐hospital cardiac arrest (OHCA) without ST‐segment elevation of possible cardiac cause by means of meta‐analysis of available randomized controlled trials (RCTs). Methods: We searched MEDLINE and the Cochrane Central Register of Controlled Trials for RCTs comparing early with delayed or selective coronary angiography in OHCA patients of possible cardiac origin without ST‐segment elevation. The primary endpoint was all‐cause short‐term mortality (PROSPERO CRD42021271484). Results: The search strategy identified three RCTs enrolling a total of 1167 patients. An early invasive approach was not associated with improved short‐term mortality (odds ratio 1.19, 95% confidence interval 0.94–1.52; p = 0.15). Further, no significant differences were shown with respect to the risk of severe neurological deficit, the composite of all‐cause mortality or severe neurological deficit, need for renal replacement therapy due to acute renal failure, and significant bleeding at short‐term follow‐up. Conclusion: Early coronary angiography in OHCA without ST‐segment elevation is not superior compared to a delayed/selective approach.
- Andere Ausgabe
- Link zur Erstveröffentlichung
Link: https://doi.org/10.1002/ccd.30355 - Freie Schlagwörter (EN)
- coronary angiography, out‐of‐hospital cardiac arrest, survival
- Klassifikation (DDC)
- 610
- Verlag
- Wiley, Hoboken
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-888481
- Veröffentlichungsdatum Qucosa
- 04.01.2024
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
- CC BY 4.0