- AutorIn
- Peter Menzel
- Peter F. Stadler
- Axel Mosig
- Titel
- Tanimoto's best barbecue
- Untertitel
- discovering regulatory modules using tanimoto scores
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-330259
- Quellenangabe
- German conference on bioinformatics GCB 2007 September 26-28, 2007, Potsdam, Germany
Erscheinungsort: Bonn
Verlag: Gesellschaft für Informatik
Erscheinungsjahr: 2007
Titel Schriftenreihe: Lecture Notes in Informatics
Bandnummer Schriftenreihe: 115
Seiten: 68-77
ISBN: 978-3-88579-209-3 - Erstveröffentlichung
- 2007
- Abstract (EN)
- We present a combinatorial method for discovering cis-regulatory modules in promoter sequences. Our approach combines “sliding window” approaches with a scoring function based on the so-called Tanimoto score. This allows to identify sets of binding sites that tend to occur preferentially in the vicinity of each other in a given set of promoter sequences belonging to co-expressed or orthologous genes. We benchmark our method on a data set derived from muscle-specific genes, demonstrating that our approach is capable of identifying modules that were identified as functional in previous studies.
- Freie Schlagwörter (EN)
- Bioinformatics
- Klassifikation (DDC)
- 004
- Version / Begutachtungsstatus
- angenommene Version / Postprint / Autorenversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-330259
- Veröffentlichungsdatum Qucosa
- 05.02.2019
- Dokumenttyp
- Konferenzbeitrag
- Sprache des Dokumentes
- Englisch