- AutorIn
- Dominic Rose
- Julian Jöris
- Jörg Hackermüller
- Kristin Reiche
- Qiang Li
- Peter F. Stadler
- Titel
- Duplicated RNA Genes in Teleost Fish Genomes
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-319501
- Quellenangabe
- Journal of Bioinformatics and Computational Biology Verlag: Imperial College Press
Erscheinungsjahr: 2008
Jahrgang: 6
Heft: 6
Seiten: 1157-1175
ISSN: 0219-7200
E-ISSN: 1757-6334 - Erstveröffentlichung
- 2008
- Abstract (EN)
- Teleost fishes share a duplication of their entire genomes. We report here on a computational survey of structured non-coding RNAs (ncRNAs) in teleost genomes, focusing on the fate of fish-specific duplicates. As in other metazoan groups, we find evidence of a large number (11,543) of structured RNAs, most of which (~86%) are clade-specific or evolve so fast that their tetrapod homologs cannot be detected. In surprising contrast to protein-coding genes, the fish-specific genome duplication did not lead to a large number of paralogous ncRNAs: only 188 candidates, mostly microRNAs, appear in a larger copy number in teleosts than in tetrapods, suggesting that large-scale gene duplications do not play a major role in the expansion of the vertebrate ncRNA inventory.
- Freie Schlagwörter (EN)
- Biochemistry, Molecular evolution, Comparative genomics, Non-coding RNA, Teleost fish
- Klassifikation (DDC)
- 572.8
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:15-qucosa2-319501
- Veröffentlichungsdatum Qucosa
- 18.10.2018
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch