- AutorIn
- Jennifer Kranz
- Stefanie Schmidt
- Cordula Lebert
- Laila Schneidewind
- Falitsa Mandraka
- Mirjam Kunze
- Sina Helbig
- Winfried Vahlensieck
- Kurt Naber
- Guido Schmiemann
- Florian M. Wagenlehner
- Titel
- The 2017 Update of the German Clinical Guideline on Epidemiology, Diagnostics, Therapy, Prevention, and Management of Uncomplicated Urinary Tract Infections in Adult Patients. Part II
- Untertitel
- Therapy and Prevention
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa2-706435
- Quellenangabe
- Urologia Internationalis Erscheinungsort: Basel
Verlag: Karger
Erscheinungsjahr: 2018
Jahrgang: 100
Heft: 3
Seiten: 271-278
ISSN: 0042-1138
E-ISSN: 1423-0399 - Erstveröffentlichung
- 2018
- Abstract (EN)
- Background: We aimed to update the 2010 evidence- and consensus-based national clinical guideline on the diagnosis and management of uncomplicated urinary tract infections (UTIs) in adult patients. Results are published in 2 parts. Part 1 covers methods, the definition of patient groups, and diagnostics. This second publication focuses on treatment of acute episodes of cystitis and pyelonephritis as well as on prophylaxis of recurrent UTIs. Materials and Methods: An interdisciplinary group consisting of 17 representatives of 12 medical societies and a patient representative was formed. Systematic literature searches were conducted in MEDLINE, EMBASE, and the Cochrane Library to identify literature published in 2010–2015. Results: For the treatment of acute uncomplicated cystitis (AUC), fosfomycin-trometamol, nitrofurantoin, nitroxoline, pivmecillinam, and trimethoprim (depending on the local rate of resistance) are all equally recommended. Cotrimoxazole, fluoroquinolones, and cephalosporins are not recommended as antibiotics of first choice, for concern of an unfavorable impact on the microbiome. Mild to moderate uncomplicated pyelonephritis should be treated with oral cefpodoxime, ceftibuten, ciprofloxacin, or levofloxacin. For AUC with mild to moderate symptoms, instead of antibiotics symptomatic treatment alone may be considered depending on patient preference after discussing adverse events and outcomes. Primarily non-antibiotic options are recommended for prophylaxis of recurrent urinary tract infection. Conclusion: In accordance with the global antibiotic stewardship initiative and considering new insights in scientific research, we updated our German clinical UTI guideline to promote a responsible antibiotic use and to give clear hands-on recommendations for the diagnosis and management of UTIs in adults in Germany for healthcare providers and patients.
- Andere Ausgabe
- Link zum Artikel der zuerst in der Zeitschrift 'Urologia Internationalis' erschienen ist
DOI: 10.1159/000487645 - Freie Schlagwörter (DE)
- Harnwegsinfektion, Zystitis, Pyelonephritis, Therapie, Systematische Überprüfung, Klinische Leitlinie
- Freie Schlagwörter (EN)
- Urinary tract infection, Cystitis, Pyelonephritis, Therapy, Systematic review, Clinical guideline
- Klassifikation (DDC)
- 610
- Verlag
- Karger, Basel
- Version / Begutachtungsstatus
- publizierte Version / Verlagsversion
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa2-706435
- Veröffentlichungsdatum Qucosa
- 26.05.2020
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis