- AutorIn
- Annemarie Kindler
- Dr. med. Barbara Seipolt
- Dr. med. Antje Heilmann
- Ursula Range
- Prof. Dr. med. Mario Rüdiger
- Dr. med. Sigrun Ruth Hofmann
- Titel
- Development of a Diagnostic Clinical Score for Hemodynamically Significant Patent Ductus Arteriosus
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-232254
- Quellenangabe
- Frontiers in Pediatrics (2017), 5, ISSN: 2296-2360. DOI: 10.3389/fped.2017.00280. Artikelnr.: 280.
- Erstveröffentlichung
- 2017
- Abstract (EN)
- There is no consensus about the hemodynamic significance and, therefore, the need to treat a persistent ductus arteriosus in preterm newborns. Since the diagnosis of a hemodynamically significant persistent ductus arteriosus (hsPDA) is made by a summary of non-uniform echo-criteria in combination with the clinical deterioration of the preterm neonate, standardized clinical and ultrasound scoring systems are needed. The objective of this study was the development of a clinical score for the detection and follow-up of hsPDA. In this observational cohort study of 154 preterm neonates (mean gestational age 28.1 weeks), clinical signs for the development of hsPDA were recorded in a standardized score and compared to echocardiography. Analyzing the significance of single score parameters compared to the diagnosis by echocardiography, we developed a short clinical score (calculated sensitivity 84% and specificity 80%). In conclusion, this clinical diagnostic PDA score is non-invasive and quickly to implement. The continuous assessment of defined clinical parameters allows for a more precise diagnosis of hemodynamic significance of PDA and, therefore, should help to detect preterm neonates needing PDA-treatment. The score, therefore, allows a more targeted use of echocardiography in these very fragile preterm neonates.
- Andere Ausgabe
- DOI: 10.3389/fped.2017.00280
- Link zum Artikel, der zuerst in der Zeitschrift 'Frontiers in Pediatrics' erschienen ist.
Link: https://doi.org/10.3389/fped.2017.00280 - Freie Schlagwörter (DE)
- arterieller Gang, klinischer Diagnosewert, Echokardiographie, Ductus arteriosus Botalli, Frühgeborene, sehr niedriges Geburtsgewicht, TU Dresden, Publikationsfond
- Freie Schlagwörter (EN)
- arterial duct, clinical diagnostic score, echocardiography, ductus arteriosus Botalli, premature infants, very low birth weight, TU Dresden, Publishing Fund
- Klassifikation (DDC)
- 610
- Klassifikation (RVK)
- XA 10000
- Verlag
- Frontiers Media, Lausanne
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-232254
- Veröffentlichungsdatum Qucosa
- 06.06.2018
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
- CC BY 4.0