- AutorIn
- Dr. Hoang Duc Luu
- Dr. Math. Joseph Páez Chávez
- Dr. Doan Thai Son
- Prof. Dr. Stefan Siegmund
- Titel
- Finite-time Lyapunov exponents and metabolic control coefficients for threshold detection of stimulus–response curves
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-215920
- Quellenangabe
- Journal of Biological Dynamics, (2016) ;10(1), S. 379-94. ISSN: 1751-3766. DOI: 10.1080/17513758.2016.1204016.
- Erstveröffentlichung
- 2016
- Abstract (EN)
- In biochemical networks transient dynamics plays a fundamental role, since the activation of signalling pathways is determined by thresholds encountered during the transition from an initial state (e.g. an initial concentration of a certain protein) to a steady-state. These thresholds can be defined in terms of the inflection points of the stimulus-response curves associated to the activation processes in the biochemical network. In the present work, we present a rigorous discussion as to the suitability of finite-time Lyapunov exponents and metabolic control coefficients for the detection of inflection points of stimulus-response curves with sigmoidal shape.
- Andere Ausgabe
- DOI: 10.1080/17513758.2016.1204016
- Link zum Artikel, der zuerst in der Zeitschrift 'Journal of Biological Dynamics' erschienen ist.
Link: http://dx.doi.org/10.1080/17513758.2016.1204016 - Freie Schlagwörter (DE)
- 37N25, Finite-time Lyapunov-Spektrum, nichtautonomes dynamisches System, sigmoidale Ansprechkurve, transiente Dynamik, TU Dresden, Publikationsfonds
- Freie Schlagwörter (EN)
- 37N25, Finite-time Lyapunov spectrum, nonautonomous dynamical system, sigmoidal response curve, transient dynamics, TU Dresden, publication fund
- Klassifikation (DDC)
- 570
- Klassifikation (RVK)
- SA 1075
- Verlag
- Taylor and Francis, London
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-215920
- Veröffentlichungsdatum Qucosa
- 19.12.2016
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis
- CC BY 4.0