- AutorIn
- Juliane Winkelmann
- Muriel Prager
- Roselind Lieb
- Hildegard Pfister
- Barbara Spiegel
- Hans-Ulrich Wittchen
- Florian Holsboer
- Claudia Trenkwalder
- Andreas Ströhle
- Titel
- "Anxietas Tibiarum"
- Untertitel
- Depression and anxiety disorders in patients with restless legs syndrome
- Zitierfähige Url:
- https://nbn-resolving.org/urn:nbn:de:bsz:14-qucosa-105372
- Quellenangabe
- Journal of Neurology, Bd. 252 (2005), Nr. 1, S. 67-71, ISSN: 0340-5354
- Erstveröffentlichung
- 2005
- Abstract (EN)
- Background: Symptoms of anxiety and depression in patients with restless legs syndrome (RLS) have been observed. However, it is unclear whether rates of threshold depression and anxiety disorders according to DSM-IV criteria in such patients are also elevated. Methods: 238 RLS patients were assessed with a standardized diagnostic interview (Munich- Composite International Diagnostic Interview for DSM-IV) validated for subjects aged 18–65 years. Rates of anxiety and depressive disorders were compared between 130 RLS patients within this age range and 2265 community respondents from a nationally representative sample with somatic morbidity of other types. Results: RLS patients revealed an increased risk of having 12-month anxiety and depressive disorders with particularly strong associations with panic disorder (OR=4.7; 95% CI=2.1–10.1), generalized anxiety disorder (OR=3.5; 95% CI= 1.7–7.1), and major depression (OR=2.6; 95% CI=1.5–4.4). In addition, lifetime rates of panic disorder and most depressive disorders as well as comorbid depression and anxiety disorders were considerably increased among RLS patients compared with controls. Conclusions: The results suggest that RLS patients are at increased risk of having specific anxiety and depressive disorders. Causal attributions of patients suggest that a considerable proportion of the excess morbidity for depression and panic disorder might be due to RLS symptomatology.
- Andere Ausgabe
- DOI: 10.1007/s00415-005-0604-7
- Link zur publizierten Version des Artikels, der in der Zeitschrift "Journal of Neurology" des Springer-Verlags erschienen ist.
Link: http://dx.doi.org/10.1007/s00415-005-0604-7 - Freie Schlagwörter (DE)
- Restless-Legs-Syndrom, Angststörung, Depression
- Freie Schlagwörter (EN)
- restless legs syndrome, anxiety, depression
- Klassifikation (DDC)
- 616.89
- Klassifikation (RVK)
- CU 3000, YG 5593
- Publizierende Institution
- Technische Universität Dresden, Dresden
- Förder- / Projektangaben
- URN Qucosa
- urn:nbn:de:bsz:14-qucosa-105372
- Veröffentlichungsdatum Qucosa
- 20.02.2013
- Dokumenttyp
- Artikel
- Sprache des Dokumentes
- Englisch
- Lizenz / Rechtehinweis