Abstract
A few clinic-based magnetic resonance imaging studies report an increased risk of signal abnormalities in migraineurs brain’s white matter, especially in migraine with aura subjects. A vascular genesis has been hypnotized and migraine with aura was considered an independent risk factor for stroke. Available data of magnetic resonance imaging alterations are often nonspecific and sometimes controversial. The aim of our study is to investigate migraine with aura patients with standardized brain magnetic resonance imaging to detect and to quantify the presence of white matter lesions and to analyze their relation with clinical data. We report preliminary data about first 90 subjects. We did not recognize any clinical aspect in close relationship with these alterations. The only clinical feature that seems to play a role in the presence of alterations is the age, and only in migraineurs women.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Lipton RB et al (1998) Medical consultation for migraine: results from the American Migraine Study. Headache 38(2):87–96
Friedman BW et al (2009) Use of emergency department for severe headache. A population-based study. Headache 49:21–30
Ferrante T et al (2012) The PACE study: past-years prevalence of migraine in Parma’s adult general population. Cephalalgia 32(5):358–365
Merikangas KR (2013) Contributions of epidemiology to our understanding of migraine. Headache 53(2):230–246
Leonardi M et al (2005) The global burden of migraine: measuring disability in headache disorders with WHO’s Classification of Functioning, Disability and Health (ICF). J Headache Pain 6(6):429–440
Kruit MC et al (2004) Migraine as a risk factor for subclinical brain lesions. JAMA 291(4):427–434
Kruit MC et al (2005) Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study. Brain 128(Pt 9):2068–2077
Scurks et al (2009) Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ 27(339):b3914
Rozen TD et al (2007) Vanishing cerebellar infarcts in a migraine patient. Cephalalgia 27(6):557–560
Rozen TD et al (2010) Images from headache: white matter lesions of migraine are not static. Headache 50(2):305–306
Headache Classification Committee of the International Headache Society—HIS (2013) The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 33(9):629–808
Acknowledgements
This study has been performed with the economical support of F.I.Cef.—Fondazione Italiana Cefalee Onlus. A special thank to Ilaria Spiezia and Virginia Invernizzi for their technical and organizing support.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors certify that there is no actual or potential conflict of interest in relation to this study.
Rights and permissions
About this article
Cite this article
Galli, A., Di Fiore, P., D’Arrigo, G. et al. Migraine with aura white matter lesions: preliminary data on clinical aspects. Neurol Sci 38 (Suppl 1), 7–10 (2017). https://doi.org/10.1007/s10072-017-2917-6
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10072-017-2917-6