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Pregnancy After Roux en Y Gastric Bypass: Nutritional and Biochemical Aspects

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Abstract

Introduction

Although pregnancy after bariatric surgery is related to risk reduction, nutritional complications may occur. This study aimed to evaluate nutritional and biochemical indicators of women who became pregnant after Roux en Y gastric bypass (RYGB).

Materials and Methods

We carried out a retrospective study with women who became pregnant after RYGB. We evaluated anthropometric, biochemical, and dietary intake indicators in the preoperative period and before, during, and after pregnancy by analysis of medical records. Shapiro-Wilk test and ANOVA for repeated measures were performed (p < 0.05).

Results

The study included 25 patients (35.7 ± 3.8 years), who became pregnant 31.3 ± 21.7 months after RYGB. Weight loss until the beginning of pregnancy was 32.4%, and the gestational weight gain was 3.8 ± 12 kg. There was a higher frequency of patients with hypertension in the preoperative time when compared to that during the pregnancy period. Total cholesterol (180.9 ± 24.8 versus 148.5 ± 30.4 mg/dL), LDL-cholesterol (103.5 ± 19.2 versus 85.8 ± 23.1 mg/dL), HDL-cholesterol (56.4 ± 8 versus 46.9 ± 8.7 mg/dL), and latent iron-binding capacity (337.6 ± 95.8 versus 277.8 ± 65 μg/dL) were higher during the pregnancy compared to that before the pregnancy, while hemoglobin values (11.2 ± 1 versus 12.3 ± 1.2 g/dL) and sodium (138.8 ± 2.9 versus 141 ± 3 mmol/L) were lower. No differences of food intake were found among times. There is no difference on gestational weight gain between women who became pregnant before or after the first year.

Conclusion

During pregnancy, there was an expected weight gain and maintenance of the lipid profile within the normal range; however, there was a reduction of hemoglobin levels. These findings show the need for individualized follow-up with adequate nutritional intervention in the event of deficiencies.

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Acknowledgements

The authors thank the São Paulo Research Foundation (FAPESP) for financial support (grant no. 2014/11603-0).

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Authors and Affiliations

  1. Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto—FMRP, Laboratory of Nutrigenomic Studies, University of São Paulo—USP, Av Bandeirantes, 3900, Monte Alegre, Ribeirao Preto, SP, 14049-900, Brazil

    Jessica Cristina Gimenes, Carolina Ferreira Nicoletti, Marcela Augusta de Souza Pinhel, Bruno Affonso Parenti de Oliveira, Júlio Sérgio Marchini & Carla Barbosa Nonino

  2. Department of Surgery and Anatomy, Faculty of Medicine of Ribeirao Preto—FMRP, University of Sao Paulo—USP, Ribeirao Preto, SP, Brazil

    Wilson Salgado Júnior

Authors
  1. Jessica Cristina Gimenes
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  2. Carolina Ferreira Nicoletti
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  3. Marcela Augusta de Souza Pinhel
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  4. Bruno Affonso Parenti de Oliveira
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  5. Wilson Salgado Júnior
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  6. Júlio Sérgio Marchini
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  7. Carla Barbosa Nonino
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Correspondence to Carla Barbosa Nonino.

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The authors declare that they have no conflict of interest.

Statement of Informed Consent

Informed consent was obtained from all individual participants included in the study.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Gimenes, J.C., Nicoletti, C.F., de Souza Pinhel, M.A. et al. Pregnancy After Roux en Y Gastric Bypass: Nutritional and Biochemical Aspects. OBES SURG 27, 1815–1821 (2017). https://doi.org/10.1007/s11695-017-2558-0

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  • DOI: https://doi.org/10.1007/s11695-017-2558-0

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