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Effect of Al:Mo molar ratio on elution performance of 99Mo/99mTc generators based on Al99Mo gels

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Abstract

Aluminum 99Mo-molybdate (VI) gels were prepared by dissolving inactive MoO3 and AlCl3·6H2O in NaOH solution containing 99Mo radiotracer at different Al:Mo molar ratios, then, the precipitation occurred using HCl acid. Characterization of the matrices was carefully investigated. Variation in Al:99Mo ratio gives different polymolybdate (VI) arrangements around the alumina fine particles. The elution efficiencies of 99mTc eluates from the corresponding gel matrices with physiological saline solution increased with increasing Mo content, which was accompanied with slightly increase in 99Mo breakthrough values. The applied chromatographic columns have been modified to introduce 99Mo/99mTc generators of high 99Mo content and high 99mTc performance.

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Acknowledgments

The authors would like to thank Prof. Dr. M. A. El Absy and Dr. T. Fasih, (Radioactive isotopes and Generators Dept. Hot Labs Center. Egyptian Atomic Energy Authority) for their support and encouragement.

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Authors and Affiliations

  1. Radioactive Isotopes and Generators Department, Hot Labs. Center, Atomic Energy Authority, Cairo, 13759, Egypt

    M. Amin

  2. Environmental Radioactive Pollution Department, Hot Labs. Center, Atomic Energy Authority, Cairo, 13759, Egypt

    E. A. Abdel-Galil & W. M. El-Kenany

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  1. M. Amin
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  2. E. A. Abdel-Galil
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  3. W. M. El-Kenany
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Correspondence to M. Amin.

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Amin, M., Abdel-Galil, E.A. & El-Kenany, W.M. Effect of Al:Mo molar ratio on elution performance of 99Mo/99mTc generators based on Al99Mo gels. J Radioanal Nucl Chem 309, 485–492 (2016). https://doi.org/10.1007/s10967-015-4656-6

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