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Effect of daily setup errors on individual dose distribution in conventional radiotherapy: an initial study

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Abstract

Recent linear accelerators can perform cone-beam computed tomography to correct setup errors immediately before dose delivery. We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradiated in the neck, esophagus, and pelvic area were obtained retrospectively. We found that the maximum dose variances for the three cases were 19.9–35.9%. The maximum dose variance points were relatively far from the isocenter. The volume of the 10% dose difference had widths of 1.3–1.85 cm around the beam edges. The V95 and mean doses at the clinical target volume were mostly unchanged. Doses around the beam edges were more varied than those around the isocenter for every case. The dose on the spinal cord located near the beam edges varied by 5–10% compared with the dose of the radiotherapy plan in two of the cases. We demonstrated the individual dose distributions of the cases affected by daily setup errors for all fractions.

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Authors and Affiliations

  1. Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan

    Akihiro Takemura & Masayuki Suzuki

  2. Kanazawa University Hospital, 1-13 Takaramachi, Kanazawa, 920-8641, Japan

    Saori Shoji, Sinichi Ueda & Yuichi Kurata

  3. Department of Radiology, Graduate School of Medical Science, Kanazawa University, 1-13 Takaramachi, Kanazawa, 920-8641, Japan

    Tomoyasu Kumano & Shigeyuki Takamatsu

Authors
  1. Akihiro Takemura
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  2. Saori Shoji
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  3. Sinichi Ueda
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  4. Yuichi Kurata
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  5. Tomoyasu Kumano
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  6. Shigeyuki Takamatsu
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  7. Masayuki Suzuki
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Correspondence to Akihiro Takemura.

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Takemura, A., Shoji, S., Ueda, S. et al. Effect of daily setup errors on individual dose distribution in conventional radiotherapy: an initial study. Radiol Phys Technol 2, 151–158 (2009). https://doi.org/10.1007/s12194-009-0059-0

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  • DOI: https://doi.org/10.1007/s12194-009-0059-0

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