Abstract
Purpose
Sublingual varicose veins are a common vascular lesion with different names, such as caviar tongue or vascular malformations. This study aimed to investigate whether there is an association between sublingual varicose veins and cardiovascular diseases by observing arterial hypertension, diabetes, thrombosis, and infarction. In addition, to evaluate a series of thrombi that affected the oral cavity and to analyze their clinical aspects and relate them to possible systemic alterations.
Methods
This is a cross-sectional study consisting of a sample of 134 varicosities, 23 vascular malformations, and 4 thrombosis.
Results
Lingual varicosities are more frequently observed in women aged 57.4 ± 16.4 years. Hypertension was present in lingual varicosities (n = 73), as well as diabetes (n = 107), reports of thrombosis (n = 41), and infarction (n = 45). Arterial hypertension was decompensated (n = 12). The most frequent underlying diseases were diabetes (p < 0.001), infarction (p = 0.012), and thrombosis (p = 0.004), and the most commonly used drug was losartan.
Conclusion
It can be inferred from the present study that lingual varicosities are related to cardiovascular diseases and can serve as a parameter to measure their decompensation.
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Data availability
All data related to this research are available in the present research and by research group.
References
Bergh H, Kastberg C, Albrektson M, Hedström L (2022) Persistence and stability of sublingual varices over time and their connection to underlying factors: an 8 year follow up study. BMC Oral Health 22(1):346
Akkaya N, Ölmez D, Özkan G (2019) Evaluation of the factors associated with sublingual varices: a descriptive clinical study. Folia Morphol (Warsz) 78(2):325–330
Duarte NT, Godoy AO, Tenório JR, Andrade NS, Franco JB, Pérez-Sayáns M, Ortega KL (2020) Prevalence of sublingual varices in patients with cirrhosis and the correlation with nitrogen compounds. Oral Surg Oral Med Oral Pathol Oral Radiol 129(1):39–44
Accardo A, Pascazio L, Costantinides F, Gorza F, Silveri G (2021) Influence of hypertension and other risk factors on the onset of sublingual varices. BMC Oral Health 21(1):235. https://doi.org/10.1186/s12903-021-01604-1
Ettinger RL, Manderson RD (1974) A clinical study of sublingual varices. Oral Surg Oral Med Oral Pathol 38(4):540–545
Tobouti PL, Pigatti FM, Martins-Mussi MC, Machado de Sousa SCO (2017) Oral thrombus: report of 122 cases with clinically descriptive data. Med Oral Patol Oral Cir Bucal 22(3):366–370
Sethia R, Allarakhia Z, Puram S, Kang S, Ozer E, Agrawal A, Carrau R, Rocco J, Old M (2019) Free flap salvage from venous thrombosis by creation of a venocutaneous fistula: case report and review of the literature. Head Neck 41(12):E159–E162. https://doi.org/10.1002/hed.25957
Heit JA (2015) Epidemiology of venous thromboembolism. Nat Rev Cardiol 12:464–474
Vishalakshi V, Nair S, Chavan N, Torsekar R (2011) Caviar tongue. Indian J Dermatol Venereol Leprol 77(1):78–79
Jafari A, Alaee A, Rezai M, Masoudi M (2022) Evaluation of sublingual varices prevalence and its respective factors in two Iranian nursing homes in 2019. Iran J Otorhinolaryngol 34(123):165–169. https://doi.org/10.22038/IJORL.2022.63364.3170
Lazos J, Marco ER, Brunotto M, Panico R, Piemonte E (2020) Oral varicose veins: Clinical features and its association with medical conditions. J Oral Maxillofac Surg Med Pathol 32(3):216–221. https://doi.org/10.1016/j.ajoms.2019.11.007
Migliari D, Vieira RR, Nakajima EK, Azevedo LH (2015) Successful management of lip and oral venous varices by photocoagulation with Nd:YAG laser. J Contemp Dent Pract 16(9):723–726. https://doi.org/10.5005/jp-journals-10024-1747
Baharvand M, Mortazavi H, Eshaghian M, Mirzaei H (2022) Sublingual varicosity as a possible indicator of hypertension. Gen Dent 70(2):46–49
World Health Organization. Global report on hypertension. The race against a silent killer, 2023. Acessado em 11 de novembro de 2023. Disponível em: https://www.who.int/publications/i/item/9789240081062
Southam JC, Ettinger RL (1974) A histologic study of sublingual varices. Oral Surg Oral Med Oral Pathol 38(6):879–886
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Funding was provided by Centro Universitário CESMAC.
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Authors Anne Caroline dos Santos Barbosa, Daniela Ignacia Rivera Palma, Ana Karolina Leão Silva Costa and Maria Karoline Santos Silva Melo wrote the frst draft of the manuscript; Authors Anne Caroline dos Santos Barbosa, Maria Karoline Santos Silva Melo and Glória Maria de França wrote the fnal version of the manuscript; Glória Maria de França took care of the clinical study; Glória Maria de França took care of the histological processes; Daniela Ignacia Rivera Palma selected the images. All authors reviewed the manuscript.
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The protocol of the study was approved on November 9, 2022 by the Ethical Committee of the Centro Universitário CESMAC by protocol number 5,749,927/2022.
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dos Santos Barbosa, A.C., Palma, D.I.R., Melo, M.K.S.S. et al. Cross-sectional study of sublingual varicosities: systemic exposures. Oral Maxillofac Surg (2023). https://doi.org/10.1007/s10006-023-01202-1
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DOI: https://doi.org/10.1007/s10006-023-01202-1