Article
Quality of life after neuro-surgery for haemangioblastoma – Von-Hippel-Lindau-Disease (VHL) versus Non-Von-Hippel-Lindau-Disease (NVHL)
Lebensqualität nach Hämangioblastom-Operation in der Neurochirurgie – Von-Hippel-Lindau-Syndrom (VHL) versus Nicht-Von-Hippel-Lindau-Syndrom (NVHL)
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Published: | June 26, 2020 |
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Objective: This study focuses on life quality of patients after operations for hemangio-blastoma, with particular regard to von-Hippel-Lindau disease.
Methods: Retrospective study of patients operated for hemangioblastoma in a tertiary neurosurgical centre in the period from 2003 to 2018. All patients were asked to fill out modified Short Form (36) Health Surveys (SF-36) to assess current quality of life (QoL).
Results: 70 patients operated for one or multiple hemangioblastomas were identified. Out of these 9 patients were dead, 10 not contactable, 2 domiciled abroad and one patient not of legal age. A total of 40 patients, 22 male and 18 female with an average age of 59.6 years replied tot he query. 85% of these patients had a cerebellar, 12.5% a spinal cord and 2.5% a brainstem location. Participation in the study was averagely 78.4 months after the latest hemangioblastoma surgery. 12 patients (30%) currently suffer from von-Hippel-Lindau disease. NVHL-patients showed a physical sum score of 44,23% on SF-36 while VHL-patients averaged 46,83% (P= -0,679). In Mental Sum Score patients without VHL-disease reached 44,23% whereas VHL-patients reached 46,83% (P= -0,03).
Conclusion: The present study showed no differences in quality of life of VHL-patients vs. Non-VHL-patients. Although von-Hippel-Lindau patients suffer from an incurable disease and often undergo multiple surgeries, they have potential to attain good quality of life. This information is helpful for patient counseling and organization of psycho-oncological care.