Postmortem CT Angiography Compared with Autopsy: A Forensic Multicenter Study.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_C21F97143C09
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Postmortem CT Angiography Compared with Autopsy: A Forensic Multicenter Study.
Journal
Radiology
Author(s)
Grabherr S., Heinemann A., Vogel H., Rutty G., Morgan B., Woźniak K., Dedouit F., Fischer F., Lochner S., Wittig H., Guglielmi G., Eplinius F., Michaud K., Palmiere C., Chevallier C., Mangin P., Grimm J.M.
ISSN
1527-1315 (Electronic)
ISSN-L
0033-8419
Publication state
Published
Issued date
07/2018
Peer-reviewed
Oui
Volume
288
Number
1
Pages
270-276
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Multicenter Study
Publication Status: ppublish
Abstract
Purpose To determine if postmortem computed tomography (CT) and postmortem CT angiography help to detect more lesions than autopsy in postmortem examinations, to evaluate the strengths and weaknesses of each method, and to define their indications. Materials and Methods Postmortem CT angiography was performed on 500 human corpses and followed by conventional autopsy. Nine centers were involved. All CT images were read by an experienced team including one forensic pathologist and one radiologist, blinded to the autopsy results. All findings were recorded for each method and categorized by anatomic structure (bone, organ parenchyma, soft tissue, and vascular) and relative importance in the forensic case (essential, useful, and unimportant). Results Among 18 654 findings, autopsies helped to identify 61.3% (11 433 of 18 654), postmortem CT helped to identify 76.0% (14 179 of 18 654), and postmortem CT angiography helped to identify 89.9% (16 780 of 18 654; P < .001). Postmortem CT angiography was superior to autopsy, especially at helping to identify essential skeletal lesions (96.1% [625 of 650] vs 65.4% [425 of 650], respectively; P < .001) and vascular lesions (93.5% [938 of 1003] vs 65.3% [655 of 1003], respectively; P < .001). Among the forensically essential findings, 23.4% (1029 of 4393) were not detected at autopsy, while only 9.7% (428 of 4393) were missed at postmortem CT angiography (P < .001). The best results were obtained when postmortem CT angiography was combined with autopsy. Conclusion Postmortem CT and postmortem CT angiography and autopsy each detect important lesions not detected by the other method. More lesions were identified by combining postmortem CT angiography and autopsy, which may increase the quality of postmortem diagnosis. Online supplemental material is available for this article.
Keywords
Adult, Aged, Aged, 80 and over, Autopsy/methods, Autopsy/statistics & numerical data, Cause of Death, Computed Tomography Angiography/methods, Computed Tomography Angiography/statistics & numerical data, Europe, Female, Forensic Pathology/methods, Humans, Male, Middle Aged, Prospective Studies, Reproducibility of Results, Young Adult
Pubmed
Web of science
Open Access
Yes
Create date
02/05/2018 13:56
Last modification date
20/08/2019 15:37
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