Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses.

Details

Ressource 1Download: BIB_B9F092E637B9.P001.pdf (266.71 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_B9F092E637B9
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
UNIL/CHUV
Title
Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses.
Journal
Open Forum Infectious Diseases
Author(s)
Kinloch-de Loes S., Dorrell L., Yang H., Hardy G.A., Yerly S., Cellerai C., Vandekerckhove L., De Spielgelaere W., Malatinkova E., Wee Lee Koh W., Johnson M.A.
ISSN
2328-8957 (Electronic)
ISSN-L
2328-8957
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
2
Number
4
Pages
ofv144
Language
english
Abstract
Combination antiretroviral therapy during primary human immunodeficiency virus-1 infection may enable long-term drug-free virological control in rare individuals. We describe a female who maintained aviremia and a normal CD4(+)/CD8(+) T cell ratio for 10 years after stopping therapy, despite a persistent viral reservoir. Cellular immune responses may have contributed to this outcome.
URN
urn:nbn:ch:serval-BIB_B9F092E637B92
OAI-PMH
oai:serval.unil.ch:BIB_B9F092E637B9
DOI
10.1093/ofid/ofv144
Pubmed
26613092
Open Access
Yes
Create date
21/06/2016 20:16
Last modification date
20/08/2019 16:27
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