Direct in vitro comparison of six three-dimensional positive contrast methods for susceptibility marker imaging.

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Serval ID
serval:BIB_B9945880FAC5
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Direct in vitro comparison of six three-dimensional positive contrast methods for susceptibility marker imaging.
Journal
Journal of Magnetic Resonance Imaging
Author(s)
Vonken E.J., Schär M., Yu J., Bakker C.J., Stuber M.
ISSN
1522-2586 (Electronic)
ISSN-L
1053-1807
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
38
Number
2
Pages
344-357
Language
english
Notes
Publication types: Comparative Study ; Evaluation Studies ; Journal Article ; Research Support, N.I.H., ExtramuralPublication Status: ppublish
Abstract
PURPOSE: To compare different techniques for positive contrast imaging of susceptibility markers with MRI for three-dimensional visualization. As several different techniques have been reported, the choice of the suitable method depends on its properties with regard to the amount of positive contrast and the desired background suppression, as well as other imaging constraints needed for a specific application.
MATERIALS AND METHODS: Six different positive contrast techniques are investigated for their ability to image at 3 Tesla a single susceptibility marker in vitro. The white marker method (WM), susceptibility gradient mapping (SGM), inversion recovery with on-resonant water suppression (IRON), frequency selective excitation (FSX), fast low flip-angle positive contrast SSFP (FLAPS), and iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) were implemented and investigated.
RESULTS: The different methods were compared with respect to the volume of positive contrast, the product of volume and signal intensity, imaging time, and the level of background suppression. Quantitative results are provided, and strengths and weaknesses of the different approaches are discussed.
CONCLUSION: The appropriate choice of positive contrast imaging technique depends on the desired level of background suppression, acquisition speed, and robustness against artifacts, for which in vitro comparative data are now available.
Keywords
Algorithms, Brain/anatomy & histology, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Imaging, Three-Dimensional/methods, Magnetic Resonance Imaging/instrumentation, Magnetic Resonance Imaging/methods, Phantoms, Imaging, Reproducibility of Results, Sensitivity and Specificity
Pubmed
Web of science
Open Access
Yes
Create date
21/01/2013 10:36
Last modification date
20/08/2019 15:27
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