Systematic review of economic analyses in patient safety: a protocol designed to measure development in the scope and quality of evidence.

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State: Public
Version: Final published version
Serval ID
serval:BIB_B8C5FD3ABF29
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Systematic review of economic analyses in patient safety: a protocol designed to measure development in the scope and quality of evidence.
Journal
BMJ open
Author(s)
Carter A.W., Mandavia R., Mayer E., Marti J., Mossialos E., Darzi A.
ISSN
2044-6055 (Electronic)
ISSN-L
2044-6055
Publication state
Published
Issued date
18/08/2017
Peer-reviewed
Oui
Volume
7
Number
8
Pages
e017089
Language
english
Abstract
Recent avoidable failures in patient care highlight the ongoing need for evidence to support improvements in patient safety. According to the most recent reviews, there is a dearth of economic evidence related to patient safety. These reviews characterise an evidence gap in terms of the scope and quality of evidence available to support resource allocation decisions. This protocol is designed to update and improve on the reviews previously conducted to determine the extent of methodological progress in economic analyses in patient safety.
A broad search strategy with two core themes for original research (excluding opinion pieces and systematic reviews) in 'patient safety' and 'economic analyses' has been developed. Medline, Econlit and National Health Service Economic Evaluation Database bibliographic databases will be searched from January 2007 using a combination of medical subject headings terms and research-derived search terms (see table 1). The method is informed by previous reviews on this topic, published in 2012. Screening, risk of bias assessment (using the Cochrane collaboration tool) and economic evaluation quality assessment (using the Drummond checklist) will be conducted by two independent reviewers, with arbitration by a third reviewer as needed. Studies with a low risk of bias will be assessed using the Drummond checklist. High-quality economic evaluations are those that score >20/35. A qualitative synthesis of evidence will be performed using a data collection tool to capture the study design(s) employed, population(s), setting(s), disease area(s), intervention(s) and outcome(s) studied. Methodological quality scores will be compared with previous reviews where possible. Effect size(s) and estimate uncertainty will be captured and used in a quantitative synthesis of high-quality evidence, where possible.
Formal ethical approval is not required as primary data will not be collected. The results will be disseminated through a peer-reviewed publication, presentations and social media.
CRD42017057853.
Keywords
Cost-Benefit Analysis, Humans, Patient Safety/economics, Research Design, health economics, health policy, patient safety, quality in health care
Pubmed
Web of science
Open Access
Yes
Create date
18/05/2018 10:16
Last modification date
20/08/2019 15:26
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