A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

Purps, J.; Siegert, S.; Willuweit, S.; Nagy, M.; Alves, C.; Salazar, R.; Angustia, S.M.; Santos, L.H.; Anslinger, K.; Bayer, B.; Ayub, Q.; Wei, W.; Xue, Y.; Tyler-Smith, C.; Bafalluy, M.B.; Martínez-Jarreta, B.; Egyed, B.; Balitzki, B.; Tschumi, S.; Ballard, D.; Court, D.S.; Barrantes, X.; Bäßler, G.; Wiest, T.; Berger, B.; Niederstätter, H.; Parson, W.; Davis, C.; Budowle, B.; Burri, H.; Borer, U.; Koller, C.; Carvalho, E.F.; Domingues, P.M.; Chamoun, W.T.; Coble, M.D.; Hill, C.R.; Corach, D.; Caputo, M.; D'Amato, M.E.; Davison, S.; Decorte, R.; Larmuseau, M.H.; Ottoni, C.; Rickards, O.; Lu, D.; Jiang, C.; Dobosz, T.; Jonkisz, A.; Frank, W.E.; Furac, I.; Gehrig, C.; Castella, V.; Grskovic, B.; Haas, C.; Wobst, J.; Hadzic, G.; Drobnic, K.; Honda, K.; Hou, Y.; Zhou, D.; Li, Y.; Hu, S.; Chen, S.; Immel, U.D.; Lessig, R.; Jakovski, Z.; Ilievska, T.; Klann, A.E.; García, C.C.; de Knijff, P.; Kraaijenbrink, T.; Kondili, A.; Miniati, P.; Vouropoulou, M.; Kovacevic, L.; Marjanovic, D.; Lindner, I.; Mansour, I.; Al-Azem, M.; Andari, A.E.; Marino, M.; Furfuro, S.; Locarno, L.; Martín, P.; Luque, G.M.; Alonso, A.; Miranda, L.S.; Moreira, H.; Mizuno, N.; Iwashima, Y.; Neto, R.S.; Nogueira, T.L.; Silva, R.; Nastainczyk-Wulf, M.; Edelmann, J.; Kohl, M.; Nie, S.; Wang, X.; Cheng, B.; Núñez, C.; Pancorbo, M.M.; Olofsson, J.K.; Morling, N.; Onofri, V.; Tagliabracci, A.; Pamjav, H.; Volgyi, A.; Barany, G.; Pawlowski, R.; Maciejewska, A.; Pelotti, S.; Pepinski, W.; Abreu-Glowacka, M.; Phillips, C.; Cárdenas, J.; Rey-Gonzalez, D.; Salas, A.; Brisighelli, F.; Capelli, C.; Toscanini, U.; Piccinini, A.; Piglionica, M.; Baldassarra, S.L.; Ploski, R.; Konarzewska, M.; Jastrzebska, E.; Robino, C.; Sajantila, A.; Palo, J.U.; Guevara, E.; Salvador, J.; Ungria, M.C.; Rodriguez, J.J.; Schmidt, U.; Schlauderer, N.; Saukko, P.; Schneider, P.M.; Sirker, M.; Shin, K.J.; Oh, Y.N.; Skitsa, I.; Ampati, A.; Smith, T.G.; Calvit, L.S.; Stenzl, V.; Capal, T.; Tillmar, A.; Nilsson, H.; Turrina, S.; De Leo, D.; Verzeletti, A.; Cortellini, V.; Wetton, J.H.; Gwynne, G.M.; Jobling, M.A.; Whittle, M.R.; Sumita, D.R.; Wolańska-Nowak, P.; Yong, R.Y.; Krawczak, M.; Nothnagel, M.; Roewer, L.

doi:10.1016/j.fsigen.2014.04.008

A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

Details

Download: 24854874.pdf (1157.25 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0

Serval ID

serval:BIB_AB35A4C32A84

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

Journal

Forensic Science International. Genetics

Author(s)

Purps J., Siegert S., Willuweit S., Nagy M., Alves C., Salazar R., Angustia S.M., Santos L.H., Anslinger K., Bayer B., Ayub Q., Wei W., Xue Y., Tyler-Smith C., Bafalluy M.B., Martínez-Jarreta B., Egyed B., Balitzki B., Tschumi S., Ballard D., Court D.S., Barrantes X., Bäßler G., Wiest T., Berger B., Niederstätter H., Parson W., Davis C., Budowle B., Burri H., Borer U., Koller C., Carvalho E.F., Domingues P.M., Chamoun W.T., Coble M.D., Hill C.R., Corach D., Caputo M., D'Amato M.E., Davison S., Decorte R., Larmuseau M.H., Ottoni C., Rickards O., Lu D., Jiang C., Dobosz T., Jonkisz A., Frank W.E., Furac I., Gehrig C., Castella V., Grskovic B., Haas C., Wobst J., Hadzic G., Drobnic K., Honda K., Hou Y., Zhou D., Li Y., Hu S., Chen S., Immel U.D., Lessig R., Jakovski Z., Ilievska T., Klann A.E., García C.C., de Knijff P., Kraaijenbrink T., Kondili A., Miniati P., Vouropoulou M., Kovacevic L., Marjanovic D., Lindner I., Mansour I., Al-Azem M., Andari A.E., Marino M., Furfuro S., Locarno L., Martín P., Luque G.M., Alonso A., Miranda L.S., Moreira H., Mizuno N., Iwashima Y., Neto R.S., Nogueira T.L., Silva R., Nastainczyk-Wulf M., Edelmann J., Kohl M., Nie S., Wang X., Cheng B., Núñez C., Pancorbo M.M., Olofsson J.K., Morling N., Onofri V., Tagliabracci A., Pamjav H., Volgyi A., Barany G., Pawlowski R., Maciejewska A., Pelotti S., Pepinski W., Abreu-Glowacka M., Phillips C., Cárdenas J., Rey-Gonzalez D., Salas A., Brisighelli F., Capelli C., Toscanini U., Piccinini A., Piglionica M., Baldassarra S.L., Ploski R., Konarzewska M., Jastrzebska E., Robino C., Sajantila A., Palo J.U., Guevara E., Salvador J., Ungria M.C., Rodriguez J.J., Schmidt U., Schlauderer N., Saukko P., Schneider P.M., Sirker M., Shin K.J., Oh Y.N., Skitsa I., Ampati A., Smith T.G., Calvit L.S., Stenzl V., Capal T., Tillmar A., Nilsson H., Turrina S., De Leo D., Verzeletti A., Cortellini V., Wetton J.H., Gwynne G.M., Jobling M.A., Whittle M.R., Sumita D.R., Wolańska-Nowak P., Yong R.Y., Krawczak M., Nothnagel M., Roewer L.

ISSN

1878-0326 (Electronic)

ISSN-L

1872-4973

Publication state

Published

Issued date

2014

Peer-reviewed

Oui

Volume

Pages

12-23

Language

english

Notes

Publication types: Journal Article ; Research Support, Non-U.S. Gov't

Abstract

In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.

Keywords

AMOVA, Database, Discriminatory power, Gene diversity, Population structure, Genetics, Forensic Medicine

URN

urn:nbn:ch:serval-BIB_AB35A4C32A849

OAI-PMH

oai:serval.unil.ch:BIB_AB35A4C32A84

DOI

10.1016/j.fsigen.2014.04.008

Pubmed

24854874

Web of science

000342433400002