Impact of extracardiac findings during cardiac MR on patient management and outcome.

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Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_8800769D9DFE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of extracardiac findings during cardiac MR on patient management and outcome.
Journal
Medical science monitor
Author(s)
Dunet V., Barras H., Boulanger X., Monney P., Qanadli S.D., Meuli R., Schwitter J., Beigelman-Aubry C.
ISSN
1643-3750 (Electronic)
ISSN-L
1234-1010
Publication state
Published
Issued date
06/05/2015
Peer-reviewed
Oui
Volume
21
Pages
1288-1296
Language
english
Notes
Publication types: Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't

Abstract
Cardiac magnetic resonance (CMR) is increasingly used to assess heart diseases. Relevant non-cardiac diseases may also be incidentally found on CMR images. The aim of this study was to determine the prevalence and nature of incidental extra-cardiac findings (IEF) and their clinical impact in non-selected patients referred for CMR.
MR images of 762 consecutive patients (515 men, age: 56±18 years) referred for CMR were prospectively interpreted by 2 radiologists blinded for any previous imaging study. IEFs were classified as major when requiring treatment, follow-up, or further investigation. Clinical follow-up was performed by checking hospital information records and by calling referring physicians. The 2 endpoints were: 1) non-cardiac death and new treatment related to major IEFs, and 2) hospitalization related to major IEFs during follow-up.
Major IEFs were proven in 129 patients (18.6% of the study population), 14% of those being unknown before CMR. During 15±6 month follow-up, treatment of confirmed major IEFs was initiated in 1.4%, and no non-cardiac deaths occurred. Hospitalization occurred in 8 patients (1.0% of the study population) with confirmed major IEFs and none occurred in the remaining 110 patients with unconfirmed/unexplored major IEFs (p<0.001).
Screening for major IEFs in a population referred for routine CMR changed management in 1.4% of patients. Major IEFs unknown before CMR but without further exploration, however, carried a favorable prognosis over a follow-up period of 15 months.

Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Disease Management, Female, Hospitalization, Humans, Incidental Findings, Infant, Kidney Diseases/diagnosis, Kidney Diseases/pathology, Liver Diseases/diagnosis, Liver Diseases/pathology, Lung Diseases/diagnosis, Lung Diseases/pathology, Magnetic Resonance Imaging, Male, Middle Aged, Myocardium/pathology, Prospective Studies, Single-Blind Method, Spinal Diseases/diagnosis, Spinal Diseases/pathology, Survival Analysis, Treatment Outcome, Young Adult
Pubmed
Web of science
Create date
12/05/2015 13:53
Last modification date
21/08/2019 6:09
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