Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.

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Serval ID
serval:BIB_5A02614F7662
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.
Journal
Genome Biology
Author(s)
Santuari L., Pradervand S., Amiguet-Vercher A.M., Thomas J., Dorcey E., Harshman K., Xenarios I., Juenger T.E., Hardtke C.S.
ISSN
1465-6914[electronic], 1465-6906[linking]
Publication state
Published
Issued date
2010
Volume
11
Number
1
Pages
R4
Language
english
Abstract
ABSTRACT: Identification of small polymorphisms from next generation sequencing short read data is relatively easy, but detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization signal reliably flags deletions. Interestingly, individual deletions were frequently observed in two or more of the accessions examined, suggesting that variation in gene content partly reflects a common history of deletion events.
Pubmed
Web of science
Open Access
Yes
Create date
01/03/2010 15:27
Last modification date
20/08/2019 14:13
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