First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions).

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_4FF9410CCC1B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions).
Journal
Breast cancer research and treatment
Author(s)
Rageth C.J., O'Flynn E.A., Comstock C., Kurtz C., Kubik R., Madjar H., Lepori D., Kampmann G., Mundinger A., Baege A., Decker T., Hosch S., Tausch C., Delaloye J.F., Morris E., Varga Z.
ISSN
1573-7217 (Electronic)
ISSN-L
0167-6806
Publication state
Published
Issued date
09/2016
Peer-reviewed
Oui
Volume
159
Number
2
Pages
203-213
Language
english
Notes
Publication types: Congresses
Publication Status: ppublish
Abstract
The purpose of this study is to obtain a consensus for the therapy of B3 lesions. The first International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) including atypical ductal hyperplasia (ADH), flat epithelial atypia (FEA), classical lobular neoplasia (LN), papillary lesions (PL), benign phyllodes tumors (PT), and radial scars (RS) took place in January 2016 in Zurich, Switzerland organized by the International Breast Ultrasound School and the Swiss Minimally Invasive Breast Biopsy group-a subgroup of the Swiss Society of Senology. Consensus recommendations for the management and follow-up surveillance of these B3 lesions were developed and areas of research priorities were identified. The consensus recommendation for FEA, LN, PL, and RS diagnosed on core needle biopsy or vacuum-assisted biopsy (VAB) is to therapeutically excise the lesion seen on imaging by VAB and no longer by open surgery, with follow-up surveillance imaging for 5 years. The consensus recommendation for ADH and PT is, with some exceptions, therapeutic first-line open surgical excision. Minimally invasive management of selected B3 lesions with therapeutic VAB is acceptable as an alternative to first-line surgical excision.

Keywords
Biopsy, Large-Core Needle, Breast/pathology, Breast Neoplasms/diagnosis, Carcinoma, Intraductal, Noninfiltrating/pathology, Carcinoma, Lobular/pathology, Disease Management, Female, Humans, Image-Guided Biopsy, Mammography/methods, Phyllodes Tumor/pathology, Population Surveillance/methods, Practice Guidelines as Topic, B3 lesions, Breast, Breast surgery, Consensus, Uncertain malignant potential, Vacuum-assisted biopsy
Pubmed
Web of science
Open Access
Yes
Create date
15/09/2016 20:10
Last modification date
20/08/2019 14:05
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