Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.

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Serval ID
serval:BIB_46976FDD8985
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.
Journal
Pediatric Nephrology
Author(s)
Cachat F., Bogaru A., Micheli J.L., Lepori D., Guignard J.P.
ISSN
0931-041X (Print)
ISSN-L
0931-041X
Publication state
Published
Issued date
2004
Volume
19
Number
5
Pages
544-546
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
Renal vein thrombosis and the congenital nephrotic syndrome have been associated with nephrotic-range proteinuria/nephrotic syndrome and hypertension in the newborn period. We describe a newborn with severe hypertension and proteinuria secondary to unilateral renal artery stenosis. Proteinuria completely disappeared with blood pressure control (with sodium nitroprusside and an angiotensin-converting enzyme inhibitor). Although renin was not measured, we speculate that proteinuria might have been induced by a high renin state, and was controlled by the angiotensin-converting enzyme inhibitor.
Keywords
Angiotensin-Converting Enzyme Inhibitors/therapeutic use, Antihypertensive Agents/therapeutic use, Aorta, Abdominal/physiopathology, Aorta, Abdominal/radiography, Blood Pressure/drug effects, Captopril/therapeutic use, Diuretics/therapeutic use, Female, Furosemide/therapeutic use, Humans, Hydralazine/therapeutic use, Hypertension, Renovascular/congenital, Hypertension, Renovascular/etiology, Infant, Newborn, Labetalol/therapeutic use, Magnetic Resonance Imaging, Nitroprusside/therapeutic use, Proteinuria/congenital, Proteinuria/etiology, Renal Artery Obstruction/complications, Renal Artery Obstruction/congenital
Pubmed
Web of science
Open Access
Yes
Create date
11/04/2008 12:19
Last modification date
14/02/2022 7:54
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