Influence of deep sternal wound infection on long-term survival after cardiac surgery.

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Serval ID
serval:BIB_42183842A733
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Influence of deep sternal wound infection on long-term survival after cardiac surgery.
Journal
Medical Science Monitor
Author(s)
Colombier S., Kessler U., Ferrari E., von Segesser L.K., Berdajs D.A.
ISSN
1643-3750 (Electronic)
ISSN-L
1234-1010
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
19
Pages
668-673
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: epublish
Abstract
BACKGROUND: This study aimed to investigate the influence of deep sternal wound infection on long-term survival following cardiac surgery.
MATERIAL AND METHODS: In our institutional database we retrospectively evaluated medical records of 4732 adult patients who received open-heart surgery from January 1995 through December 2005. The predictive factors for DSWI were determined using logistic regression analysis. Then, each patient with deep sternal wound infection (DSWI) was matched with 2 controls without DSWI, according to the risk factors identified previously. After checking balance resulting from matching, short-term mortality was compared between groups using a paired test, and long-term survival was compared using Kaplan-Meier analysis and a Cox proportional hazard model.
RESULTS: Overall, 4732 records were analyzed. The mean age of the investigated population was 69.3±12.8 years. DSWI occurred in 74 (1.56%) patients. Significant independent predictive factors for deep sternal infections were active smoking (OR 2.19, CI95 1.35-3.53, p=0.001), obesity (OR 1.96, CI95 1.20-3.21, p=0.007), and insulin-dependent diabetes mellitus (OR 2.09, CI95 1.05-10.06, p=0.016). Mean follow-up in the matched set was 125 months, IQR 99-162. After matching, in-hospital mortality was higher in the DSWI group (8.1% vs. 2.7% p=0.03), but DSWI was not an independent predictor of long-term survival (adjusted HR 1.5, CI95 0.7-3.2, p=0.33).
CONCLUSIONS: The results presented in this report clearly show that post-sternotomy deep wound infection does not influence long-term survival in an adult general cardio-surgical patient population.
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Web of science
Create date
08/09/2013 9:17
Last modification date
20/08/2019 13:43
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