Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment: A dangerous liaison.

Details

Ressource 1Download: BIB_36ED7FF628CE.P001.pdf (413.83 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_36ED7FF628CE
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment: A dangerous liaison.
Journal
OncoImmunology
Author(s)
Conrad C., Gilliet M.
ISSN
2162-4011 (Print)
Publication state
Published
Issued date
05/2013
Volume
2
Number
5
Pages
e23887
Language
english
Notes
Publication types: JOURNAL ARTICLEPublication Status: ppublish. pdf type: Author's View
Abstract
Tumor-infiltrating plasmacytoid dendritic cells (pDCs) have been associated with poor patient prognosis. We have recently uncovered the ability of pDCs to activate and expand a subset of tumor-infiltrating FOXP3(+) regulatory T cells that express inducible costimulator (ICOS), providing new insights into the mechanisms that govern the escape of cancer from immunosurveillance.
Pubmed
Web of science
Create date
14/02/2014 16:23
Last modification date
20/08/2019 13:25
Usage data