Successful Lung Transplant After Prolonged Extracorporeal Membrane Oxygenation (ECMO) in a Child With Pulmonary Hypertension: A Case Report.

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Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_2B9AD9DB93ED
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Title
Successful Lung Transplant After Prolonged Extracorporeal Membrane Oxygenation (ECMO) in a Child With Pulmonary Hypertension: A Case Report.
Journal
Research in cardiovascular medicine
Author(s)
Tissot C., Habre W., Soccal P., Hug M.I., Bettex D., Pellegrini M., Aggoun Y., Mornand A., Kalangos A., Rimensberger P., Beghetti M.
ISSN
2251-9572 (Print)
ISSN-L
2251-9572
Publication state
Published
Issued date
08/2016
Peer-reviewed
Oui
Volume
5
Number
3
Pages
e32545
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
The use of extracorporeal membrane oxygenation (ECMO) is considered a risk factor for, or even a potential contraindication to, lung transplantation. However, only a few pediatric cases have been described thus far.
A 9-year-old boy with idiopathic pulmonary arterial hypertension developed cardiac arrest after the insertion of a central catheter. ECMO was used as a bridge to lung transplantation. However, after prolonged resuscitation, he developed medullary ischemia and medullary syndrome. After 6 weeks of ECMO and triple combination therapy for pulmonary hypertension, including continuous intravenous prostacyclin, he was weaned off support, and after 2 weeks, bilateral lung transplantation was performed. At 4 years post-transplant, he has minimal problems. The medullary syndrome has also alleviated. He is now back to school and can walk with aids.
Increasing evidence supports the use of ECMO as a bridge to LT, reporting good outcomes. In the modern era of PAH therapy, it is feasible to use prolonged ECMO support as a bridge to lung transplant, with the aim of weaning off this support; however, its use requires more experience and knowledge of long-term outcomes.
Keywords
Extracorporeal Membrane Oxygenation (ECMO), Hypertension, Pulmonary, Lung Transplantation, Pediatrics
Pubmed
Open Access
Yes
Create date
10/01/2019 16:35
Last modification date
15/01/2021 7:08
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