High bi-atrial organization in patients with long-standing persistent atrial fibrillation terminated within the left atrium

Details

Ressource 1Download: BIB_273F654DAAEF.P001.pdf (302.08 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_273F654DAAEF
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Poster: Summary – with images – on one page of the results of a researche project. The summaries of the poster must be entered in "Abstract" and not "Poster".
Collection
Publications
Institution
Title
High bi-atrial organization in patients with long-standing persistent atrial fibrillation terminated within the left atrium
Title of the conference
EHRA EUROPACE 2013
Author(s)
Buttu A., Pruvot E., Forclaz A., Pascale P., Narayan S.M., Maury P., Rollin A., Vesin J.M.
Address
Athens, Greece, June 23-26, 2013
ISBN
1532-2092
ISSN-L
1099-5129
Publication state
Published
Issued date
2013
Volume
15
Series
Europace
Pages
P979
Language
english
Abstract
Sustained atrial fibrillation (AF) is maintained by sites displaying high dominant frequency (DF). In patients (pts) with long-standing persistent AF (LS-pAF), their spatial distribution and the presence of a left-to-right atrial DF gradient remain poorly known. We hypothesized that the pre-ablation bi-atrial frequency characteristics of LS-pAF pts terminated within the left atrium (LT) are different from that of non terminated (NT) ones. Methods: 23 consecutive pts (59±7y, LS-pAF duration 19±12m) underwent stepwise catheter ablation (step-CA) consisting in pulmonary veins isolation, left atrial (LA) defragmentation, and right atrial (RA) ablations for non terminated AF. A quadripolar catheter (CAT) was placed into the RA appendage (RAA), a decapolar CAT into the coronary sinus (CS) and a duodecapolar CAT into the LA divided into 8 segments. For each segment, 20-sec of bipolar recording was acquired. The DF was defined as the largest peak in the power spectrum (3-15 Hz). The inter-atrial DF gradient was defined as the DF difference between LA and RA appendages. Results: LS-pAF was terminated in 83% (19/23) of the pts: 17 LT, 2 during RA ablation and 4 NT. The figure shows that before ablation bi-atrial DF values of LT pts are significantly lower than that of NT pts for each LA segment as well as for the RAA (p < 0.05). No significant LA-to-RA DF gradient was observed both for LT (0.3±0.5 Hz, p=ns) and NT (0.5±0.03 Hz, p=ns) pts. No significant difference in DF values was observed between LA segments. Conclusions: The lower DF of LT pts is suggestive of a higher organization within both atria compared to NT pts. Our findings suggest that low bi-atrial DF values, but not inter-atrial DF gradient, might be of interest for selecting LS-pAF candidates for sinus rhythm restoration by step-CA.
Create date
28/08/2013 10:48
Last modification date
20/08/2019 13:06
Usage data