Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.

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Version: Final published version
Serval ID
serval:BIB_237C31A1A8A9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.
Journal
Nature Communications
Author(s)
Arguello J.R., Cardoso-Moreira M., Grenier J.K., Gottipati S., Clark A.G., Benton R.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
2016
Volume
7
Pages
ncomms11855
Language
english
Notes
Publication types: Journal ArticlePublication Status: epublish
Abstract
How organisms adapt to new environments is of fundamental biological interest, but poorly understood at the genetic level. Chemosensory systems provide attractive models to address this problem, because they lie between external environmental signals and internal physiological responses. To investigate how selection has shaped the well-characterized chemosensory system of Drosophila melanogaster, we have analysed genome-wide data from five diverse populations. By couching population genomic analyses of chemosensory protein families within parallel analyses of other large families, we demonstrate that chemosensory proteins are not outliers for adaptive divergence between species. However, chemosensory families often display the strongest genome-wide signals of recent selection within D. melanogaster. We show that recent adaptation has operated almost exclusively on standing variation, and that patterns of adaptive mutations predict diverse effects on protein function. Finally, we provide evidence that chemosensory proteins have experienced relaxed constraint, and argue that this has been important for their rapid adaptation over short timescales.
Pubmed
Web of science
Open Access
Yes
Create date
08/07/2016 8:57
Last modification date
20/08/2019 13:01
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