The InterPro database, an integrated documentation resource for protein families, domains and functional sites.

Apweiler, R.; Attwood, T.K.; Bairoch, A.; Bateman, A.; Birney, E.; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M.D.; Durbin, R.; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N.J.; Oinn, T.M.; Pagni, M.; Servant, F.; Sigrist, C.J.; Zdobnov, E.M.

doi:10.1093/nar/29.1.37

The InterPro database, an integrated documentation resource for protein families, domains and functional sites.

Details

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Serval ID

serval:BIB_18766

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

The InterPro database, an integrated documentation resource for protein families, domains and functional sites.

Journal

Nucleic acids research

Author(s)

Apweiler R., Attwood T.K., Bairoch A., Bateman A., Birney E., Biswas M., Bucher P., Cerutti L., Corpet F., Croning M.D., Durbin R., Falquet L., Fleischmann W., Gouzy J., Hermjakob H., Hulo N., Jonassen I., Kahn D., Kanapin A., Karavidopoulou Y., Lopez R., Marx B., Mulder N.J., Oinn T.M., Pagni M., Servant F., Sigrist C.J., Zdobnov E.M.

ISSN

1362-4962[electronic]

Publication state

Published

Issued date

2001

Volume

Number

Pages

37-40

Language

english

Notes

Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish

Abstract

Signature databases are vital tools for identifying distant relationships in novel sequences and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1,000,000 hits from 462,500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelp@ebi.ac.uk.

Keywords

Databases, Factual, Information Services, Internet, Protein Structure, Tertiary, Proteins

URN

urn:nbn:ch:serval-BIB_187660

OAI-PMH

oai:serval.unil.ch:BIB_18766

DOI

10.1093/nar/29.1.37

Pubmed

11125043

Web of science

000166360300007