Lausannevirus Seroprevalence among Asymptomatic Young Adults.

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Version: Author's accepted manuscript
Serval ID
serval:BIB_0EEF6820871F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Lausannevirus Seroprevalence among Asymptomatic Young Adults.
Journal
Intervirology
Author(s)
Mueller L., Baud D., Bertelli C., Greub G.
ISSN
1423-0100 (Electronic)
ISSN-L
0300-5526
Publication state
Published
Issued date
2013
Volume
56
Number
6
Pages
430-433
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Objectives: The giant Lausannevirus was recently identified as a parasite of amoeba that replicates rapidly in these professional phagocytes. This study aimed at assessing Lausannevirus seroprevalence among asymptomatic young men in Switzerland and hopefully identifying possible sources of contact with this giant virus. Methods: The presence of anti-Lausannevirus antibodies was assessed in sera from 517 asymptomatic volunteers who filled a detailed questionnaire. The coreactivity between Lausannevirus and amoeba-resisting bacteria was assessed. Results: Lausannevirus prevalence ranged from 1.74 to 2.51%. Sporadic condom use or multiple sexual partners, although frequent (53.97 and 60.35%, respectively), were not associated with anti-Lausannevirus antibodies. On the contrary, frequent outdoor sport practice as well as milk consumption were significantly associated with positive Lausannevirus serologies (p = 0.0066 and 0.028, respectively). Coreactivity analyses revealed an association between Criblamydia sequanensis (an amoeba-resisting bacterium present in water environments) and Lausannevirus seropositivity (p = 0.001). Conclusions: Lausannevirus seroprevalence is low in asymptomatic Swiss men. However, the association between virus seropositivity and frequent sport practice suggests that this member of the Megavirales may be transmitted by aerosols and/or exposure to specific outdoor environments. Milk intake was also associated with seropositivity. Whether the coreactivity observed for C. sequanensis and Lausannevirus reflects a common mode of acquisition or some unexpected cross-reactivity remains to be determined. © 2013 S. Karger AG, Basel.
Pubmed
Web of science
Open Access
Yes
Create date
01/12/2013 15:27
Last modification date
20/08/2019 12:35
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