When orthologs diverge between human and mouse.

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Ressource 1Download: BIB_006579177FCC.P001.pdf (90.56 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_006579177FCC
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
When orthologs diverge between human and mouse.
Journal
Briefings in Bioinformatics
Author(s)
Gharib W.H., Robinson-Rechavi M.
ISSN
1477-4054 (Electronic)
ISSN-L
1467-5463
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
12
Number
5
Pages
436-441
Language
english
Abstract
Despite the common assumption that orthologs usually share the same function, there have been various reports of divergence between orthologs, even among species as close as mammals. The comparison of mouse and human is of special interest, because mouse is often used as a model organism to understand human biology. We review the literature on evidence for divergence between human and mouse orthologous genes, and discuss it in the context of biomedical research.
Pubmed
Web of science
Open Access
Yes
Create date
11/05/2011 8:17
Last modification date
20/08/2019 12:22
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