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Influence of various selenium sources on selenium concentration in the milk of dairy cows

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Abstract

Selenium (Se) as essential trace element is supplemented in various compounds to rations of food producing animals. In human nutrition the range between Se requirement and upper level is very small (1:3–5). Hence, food of animal origin may contribute to Se supply of humans, but can also offer high amounts of Se and exceed the Se upper level for humans. Therefore the transfer into the milk of inorganic (0.2 and 0.4 mg Se from sodium-selenite) or organic (Se methionine) Se-compounds was tested. Fifteen lactating German Holstein cows were fed diets without supplementation (0.1 mg Se/kg dry matter, DM) or supplemented with inorganic or an organic Se-compound over 3 weeks. Se-supplementation did not significantly influence feed intake, milk yield and composition as well as animal health. Se-concentration of milk increased from 13.3 over 17.6 to 19.7 μg/L in the case of inorganic Se supplementation and from 13.9 over 24.6 to 54.8 μg/L after Se-yeast addition.

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References

  • Bennett DC, Cheng KM (2010) Selenium enrichment of table eggs. Poult Sci 89:2166–2172

    Article  CAS  PubMed  Google Scholar 

  • Calamari L, Petrera F, Bertin G (2010) Effects of either sodium selenite or Se yeast (Sc CNCM I-3060) supplementation on selenium status and milk characteristics in dairy cows. Livest Sci 128(1–3):154–165

    Article  Google Scholar 

  • Ceballos A, Sanchez J, Stryhn H, Montgomery JB, Barkema HW, Wichtel JJ (2009) Meta-analysis of the effect of oral selenium supplementation on milk selenium concentration in cattle. J Dairy Sci 92(1):324–342

    Article  CAS  PubMed  Google Scholar 

  • Cortinhas CS, de Freitas JE, Naves JD, Porcionato MAD, Silva L, Renno FP, dos Santos MV (2012) Organic and inorganic sources of zinc, copper and selenium in diets for dairy cows: intake, blood metabolic profile, milk yield and composition. Rev Bras Zootecn 41(6):1477–1483

    Article  Google Scholar 

  • DACH (2008) Referenzwerte für die Nährstoffzufuhr, Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung. Neuer Umschau Buchverlag, Neustadt/Weinstraße

  • EC (European Commission) (2000) Option of the Scientific Committee on Food on the tolerable upper intake level of selenium (expressed on 19 October 2000). http://ec.europa.eu/food/fs/sc/scf/out80g_en.pdf

  • EFSA (2006) Opinion of the scientific panel on additives and products or substances used in animal feed on the safety and efficacy of the product selenium enriched yeast (Saccharomyces cerevisiae NCYC R397) as a feed additive for all species in accordance with regulation (EC) No 1831/2003. EFSA J 430:123

    Google Scholar 

  • EFSA (2009) Safety and efficacy of SELSAF (Selenium enriched yeast from Saccharomyces cerevisiae CNCM 1-3399) as feed additive for all species. EFSA J 992:124

    Google Scholar 

  • EFSA (2011a) Scientific opinion on safety and efficacy of Sel-Plex® (organic form of selenium produced by Saccharomyces cerevisiae CNCM I-3060) for all species. EFSA J 9(4):2110

  • EFSA (2011b) Scientific opinion on the safety and efficacy of selenium in the form of organic compounds produced by the selenium-enriched yeast Saccharomyces cerevisiae NCYC R645 (SelenoSource AF 2000) for all species. EFSA J 9(6):2279

    Google Scholar 

  • EFSA (2012) Scientific opinion on safety and efficacy of selenium in the form of organic compounds produced by the selenium-enriched yeast Saccharomyces cerevisiae NCYC R646 (Selemax 1000/2000) as feed additive for all species. EFSA J 10(7):2778

    Google Scholar 

  • EFSA (2013a) Scientific opinion on safety and efficacy of hydroxy-analogue of selenomethionine as feed additive for all species. EFSA J 11(1):3046

    Google Scholar 

  • EFSA (2013b) Scientific opinion on the safety and efficacy of l-selenomethionine as feed additive for all animal species. EFSA J 11(5):3219

  • EFSA (European Food Safety Authority) (2006) Opinion of the scientific panel on additives and products or substances used in animal feed on the safety and efficacy of the product Sel-Plex®2000 as a feed additive according to Regulation (EC) No 1831/2003. EFSA J 348:1–40

    Google Scholar 

  • EU (2003) Commission Regulation (EC) No 1334/2003 of 25 July 2003 amending the conditions for authorisation of a number of additives in feedingstuffs belonging to the group of trace elements. Off J Eur Union L187/11

  • EU (2013) Commission Implementing Regulation (EU) No 427/2013 of 8 May 2003 concerning the authorisation of selenomethionine produced by Saccharomyces cerevisiae NCYC R646 as a feed additive for all animal species and amending Regulations (EC) No 1750/2006, (EC) No 634/2007 and (EC) No 900/2009 as regards the maximum supplementation with selenised yeast. Off J Eur Union L127/20

  • Gassmann B (2000) Dietary reference intakes, report 3: vitamin C, vitamin E, selenium, and carotenoids. Ernährungs-Umschau 47(7):265–270

    CAS  Google Scholar 

  • Gassmann B (2006) Zum Festlegen von Höchst- und Mindestmengen an Vitaminen und Mineralstoffen in Lebensmitteln. Ernährungs-Umschau 53:336–343

    CAS  Google Scholar 

  • GfE (2001) Empfehlungen zur Energie und Nährstoffversorgung der Milchkühe und Aufzuchtrinder. Vol. Nr. 8. Energie- und Nährstoffbedarf landwirtschaftlicher Nutztiere. DLG-Verlag, Frankfurt am Main

  • Gierus M, Schwarz FJ, Kirchgessner M (2002) Selenium supplementation and selenium status of dairy cows fed diets based on grass, grass silage or maize silage. J Anim Physiol Anim Nutr 86(3–4):74–82

    Article  CAS  Google Scholar 

  • Givens DI, Allison R, Cottrill B, Blake JS (2004) Enhancing the selenium content of bovine milk through alteration of the form and concentration of selenium in the diet of the dairy cow. J Sci Food Agr 84(8):811–817

    Article  CAS  Google Scholar 

  • Hall JA, van Saun RJ, Bobe G, Steward WC, Vorachek WR, Mosher WD, Nichols T, Forsberg NE, Pirelli GJ (2012) Organic and inorganic selenium: I. Oral bioavailability in ewes. J Anim Sci 90(2):568–576

    Article  CAS  PubMed  Google Scholar 

  • Hampel K, Schöne F, Böhm V, Leiterer M, Jahreis G (2004) Composition and nutritional importance of sheep milk and sheep milk products (in German). Deut Lebensm-Rundsch 11:425–430

    Google Scholar 

  • Hoac T, Stagsted J, Lundh T, Nielsen JH, Akesson B (2008) Short term effects of selenium supplementation of cows feed on the content and distribution of selenium, copper and zinc in bovine milk, whey and blood plasma. J Dairy Res 75:326–334

    Article  CAS  PubMed  Google Scholar 

  • Juniper DT, Phipps RH, Jones AK, Bertin G (2006) Selenium supplementation of lactating dairy cows: effect on selenium concentration in blood, milk, urine, and feces. J Dairy Sci 89(9):3544–3551

    Article  CAS  PubMed  Google Scholar 

  • Koutnik V, Kourek B, Havlicek Z (2005) Selenium content in milk of some dairy cattle herds in the South Moravian region. Zivocisna vyroba 41:473–474

    Google Scholar 

  • Kraft W, Dürr UM (2005) Klinische Labordiagnostik in der Tiermedizin. Schattauer, Stuttgart

    Google Scholar 

  • McDowell LR (2003) Minerals in animal and human nutrition, 2nd edn. Elsevier Science B.V., Amsterdam

    Google Scholar 

  • MRI (Max Rubner-Institut) (2008) Nationale Verzehrsstudie II, Ergebnisbericht, Teil 2, Karlsruhe

  • NRC (2005) Mineral tolerance of animals, 2nd edn. National Academy of Sciences/National Academic Press, Washington

    Google Scholar 

  • NRC (National Research Council), (2001) Nutrient requirements for dairy cattle, 7th edn. National Academy of Sciences/National Academic Press, Washington

    Google Scholar 

  • Ortman K, Pherson B (1999) Effect of selenate as a feed supplement to dairy cows in comparison to selenite and selenium yeast. J Anim Sci 77:3365–3370

    CAS  PubMed  Google Scholar 

  • Pavlata L, Misurova L, Pechova A, Dvorak R (2011) The effect of inorganic and organically bound forms of selenium on glutathione peroxidase activity in blood of goats. Vet Med 56:75–81

    CAS  Google Scholar 

  • Pehrson B, Ortman K, Madjid N, Trafikowska U (1999) The influence of dietary selenium as selenium yeast or sodium selenite on the concentration of selenium in the milk of suckler cows and on the selenium status of their calves. J Anim Sci 77(12):3371–3376

    CAS  PubMed  Google Scholar 

  • Rayman MP (2004) The use of high-selenium yeast to raise selenium status: how does it measure up? Br J Nutr 92(4):557–573

    Article  CAS  PubMed  Google Scholar 

  • Rey Crespo F, Miranda M, Lopez-Alonso M (2013) Essential trace and toxic element concentrations in organic and conventional milk in NW Spain. Food Chem Toxicol 55(5):513–518

    Article  CAS  PubMed  Google Scholar 

  • Rotruck JT, Pope AL, Ganther HE, Hafeman DG, Hoekstra WG (1973) Selenium biochemical role as a component of glutathione peroxidase. Science (Washington D C) 179(4073):588–590

    Article  CAS  Google Scholar 

  • Rozenska L, Hejtmankova A, Kolihova D, Miholova D (2011) Selenium and iodine content in sheep milk from farms in Central and East Bohemia. Scientia Agriculturae Bohemica 42:153–158

    Google Scholar 

  • Salam S, Dinse D, Khol-Parisoini A, Schafft H, Lahrssen-Wiederholt M, Schreiner M, Scharek-Tedin L, Zentek J (2013) Colostrum and milk selenium, antioxidative capacity and immune status of dietary cows fed sodium selenite or selenium yeast. Arch Anim Nutr 67(1):48–61

    Article  Google Scholar 

  • SCF (Scientific Committee on Food) (2000) Opinion of the Scientific Committee on Food in the tolerable upper intake level of Selenium. Document SCF/CS/NUT/UPPLEV/25 Final. Brussels, 1910.2000. http://ec.europa.eu/food/fs/sc/sct/out80g_en.pdf. Accessed 19 Apr 2008

  • Schöne F, Steinhöfel O, Weigel K, Bergmann H, Herzog E, Dunkel S, Krimse R, Leiterer M (2013) Selenium in feedstuffs and rations for dairy cows including a view of the food chain up to the consumer. J Verbr Lebensm 8(4):271–280

    Article  Google Scholar 

  • Schrauzer GN (2002) Selenomethionine: a review of its nutritional significance, metabolism and toxicity. J Nutr 132(12):1653–1656

    Google Scholar 

  • Shi L, Xun W, Yue W, Zhang C, Ren Y, Liu Q, Wang Q, Shi L (2011) Effect of elemental nano-selenium on feed digestibility, rumen fermentation, and purine derivatives in sheep. Anim Feed Sci Tech 163(2–4):136–142

    Article  CAS  Google Scholar 

  • Slavik P, Illek J, Brix M, Hlavicova J, Rajmon R, Jilek F (2008) Influence of organic versus inorganic dietary selenium supplementation on the concentration of selenium in colostrum, milk and blood of beef cows. Acta Vet Scand 50:43

    Article  PubMed Central  PubMed  Google Scholar 

  • Stewart WC, Bobe G, Vorachek WR, Pirelli GJ, Mosher WD, Nichols T, van Saun RJ, Forsberg NE, Hall JA (2012) Organic and inorganic selenium: II. Transfer efficiency from ewes to lambs. J Anim Sci 90(2):2577–2584

    Article  Google Scholar 

  • Stockdale CR, Shields PM, McKenna A, Walker GP, Dunshea FR, Doyle PT (2011) Selenium levels in cows fed pasture and concentrates or a total mixed ration and supplemented with selenized yeast to produce milk with supra-nutritional selenium concentrations. J Dairy Sci 94(1):262–272

    Article  CAS  PubMed  Google Scholar 

  • Surai PF (2006) Selenium in animal and human health. Nottingham Univ. Press, Nottingham

    Google Scholar 

  • Suttle NF (2010) Selenium. In: Mineral nutrition of livestock, 4th edn. CAB International, Wallingford, pp 377–425

  • Taylor D, Dalton C, Hall A, Woodroofe MN, Gardiner PHE (2009) Recent developments in selenium research. Br J Biomed Sci 66(2):107–116

    CAS  PubMed  Google Scholar 

  • VDLUFA (1976a) Methodenbuch Band III. Die chemische Untersuchung von Futtermitteln, 3. Auflage einschließlich 1.-8. Erg.Lief

  • VDLUFA (1976b) Methodenbuch Band III. Die chemische Untersuchung von Futtermitteln. 11.6.2. Bestimmung von Selen in Futtermitteln. Fließinjektions-Hydrid-AAS-Methode. 6. Erg.Lief. 2006

  • Walker GP, Dunshea FR, Heard JW, Stockdale CR, Doyle PT (2010) Output of selenium in milk, urine, and feces is proportional to selenium intake in dairy cows fed a total mixed ration supplemented with selenium yeast. J Dairy Sci 93(10):4644–4650

    Article  CAS  PubMed  Google Scholar 

  • Wang C, Liu Q, Yang WZ, Dong Q, Yang XM, He DC, Zhang P, Dong KH, Huang YX (2009) Effects of selenium yeast on rumen fermentation, lactation performance and feed digestibilities in lactating dairy cows. Livest Sci 126(1–3):239–244

    Article  Google Scholar 

  • Zhang JS, Gao XY, Zhang LD, Bao YP (2001) Biological effects of a nano red elemental selenium. Biofactors 15(1):27–38

    Article  PubMed  Google Scholar 

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Correspondence to Ulrich Meyer.

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Meyer, U., Heerdegen, K., Schenkel, H. et al. Influence of various selenium sources on selenium concentration in the milk of dairy cows. J. Verbr. Lebensm. 9, 101–109 (2014). https://doi.org/10.1007/s00003-014-0870-3

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  • DOI: https://doi.org/10.1007/s00003-014-0870-3

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